Balıklarda bağışıklık sistemi, mukozal bağışıklıklık ve IL-1β, IL-18 ve TNF-α proenflamatuvar sitokinlerinin işlevleri

Serdar Kilercioğlu

doi:10.12714/egejfas.38.1.16

TR EN

Balıklarda bağışıklık sistemi, mukozal bağışıklıklık ve IL-1β, IL-18 ve TNF-α proenflamatuvar sitokinlerinin işlevleri

Öz

Balık, sucul ortamda türlü tehditler ile karşılaşmakta ve bu tehditlere karşı evrimsel süreçte geliştirdiği bağışıklık yanıtları ile karşılık vermektedir. Balıklarda bağışıklık sistemi doğal ve kazanılmış bağışıklığın sıvısal ve hücresel elemanlarından oluşur. Mukoza ile ilişkili dokular da savunma sisteminin bir parçası olup doğal ve kazanılmış bağışıklığın hücreleri ile donatılmıştır. Bağışıklık sisteminin hücre ve moleküllerinin oluştuğu, olgunlaştığı ve sisteme dahil edildiği organlar lenfoid organlar olarak adlandırılmaktadır. Sitokinler, canlıda büyüme, farklılaşma ve bağışıklık yanıtı gibi birçok görev üstlenen küçük glikoproteinlerdir. Sitokinlerin, bağışıklık sistemindeki ana rolleri bağışıklık yanıtlarını düzenlemeleri ve hücreler arası iletişimi sağlamalarıdır. Bu derlemede balık bağışıklık sisteminin ana sıvısal ve hücresel bileşenleri, mukozal bağışıklık sistemi, birincil lenfoid organların işlevleri ve proenflamatuvar etki gösteren IL-1β, IL-18 ve TNF-α sitokinleri hakkında literatürde yer alan bilgiler ana hatları ile bir araya getirilmiş, bahsi geçen sitokinlerin bağışıklık sistemindeki görevlerinin anlaşılması amaçlanmıştır.

Anahtar Kelimeler

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

Yapısal Biyoloji

Bölüm

Derleme

Yazarlar

Serdar Kilercioğlu ^*
0000-0001-5288-0781
Türkiye

Yayımlanma Tarihi

15 Mart 2021

Gönderilme Tarihi

22 Nisan 2020

Kabul Tarihi

4 Ağustos 2020

Yayımlandığı Sayı

Yıl 1970 Cilt: 38 Sayı: 1

DOI

https://doi.org/10.12714/egejfas.38.1.16

IZ

https://izlik.org/JA75XK53DS

Kaynak Göster

RIS / Bibtex

APA

Kilercioğlu, S. (2021). Balıklarda bağışıklık sistemi, mukozal bağışıklıklık ve IL-1β, IL-18 ve TNF-α proenflamatuvar sitokinlerinin işlevleri. Ege Journal of Fisheries and Aquatic Sciences, 38(1), 125-134. https://doi.org/10.12714/egejfas.38.1.16

Cited By

Utilization of Fish Byproduct in Edible Films: A Sustainable Approach to Improving Fillet Shelf Life

Food Science & Nutrition

https://doi.org/10.1002/fsn3.70731

Dietary Betaine Improves Immune Function, Antioxidant Status, Immune‐Related Signaling Molecules, and Disease Resistance in Fish Species

Aquaculture Nutrition

https://doi.org/10.1155/anu/4596572

Balıklarda bağışıklık sistemi, mukozal bağışıklıklık ve IL-1β, IL-18 ve TNF-α proenflamatuvar sitokinlerinin işlevleri

Balıklarda bağışıklık sistemi, mukozal bağışıklıklık ve IL-1β, IL-18 ve TNF-α proenflamatuvar sitokinlerinin işlevleri

Öz

Anahtar Kelimeler

Fish immune system, mucosal immunity and functions of IL-1β, TNF-α and IL-18 proinflammatory cytokines

Abstract

Keywords

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

Kaynak Göster

Cited By

Utilization of Fish Byproduct in Edible Films: A Sustainable Approach to Improving Fillet Shelf Life

Dietary Betaine Improves Immune Function, Antioxidant Status, Immune‐Related Signaling Molecules, and Disease Resistance in Fish Species