Endokrin Sistemi Bozan Kimyasallardan Cinsiyet Steroidlerinin Balıklardaki Etkileri.

Şehriban Çek; Fatmagün Sarıhan

EN TR

Endokrin Sistemi Bozan Kimyasallardan Cinsiyet Steroidlerinin Balıklardaki Etkileri.

Öz

İnsanların kullanımları sonucunda oluşan ve endokrin sistemi bozan kimyasallar (EBk), omurgalılarda iç kaynaklı hormonların etkilerine benzer etkilerde bulunmakta ve endokrin sistemle karşılıklı etkileşime girebilmektedirler. EBk evsel atıkların karıştığı sularda, endüstriyel atıklarda ve çiftlik hayvanları yem artıklarında saptanmıştır. Bu atıklarla kirlenmiş olan sularda yaşayan balıkların üreme sistemlerinde bozukluklar olduğu görülmüştür. EBk’ın zararlı etkiler; ayrıca kurbağalarda, sürüngenlerde, kuşlarda, memelilerde ve insanlarda da kaydedilmiştir. Doğal östrojen 17β-östradiol (E2), balıkların karaciğerini, vitellogenin (Vtg) sentezlemesi için uyarır. Vitellogenin yumurtanın olgunlaşmasını sağlayan proteindir. 17α-ethinylestradiol (EE2), çok güçlü sentetik bir östrojendir ve tüm dünyada doğum kontrol tableti olarak kullanılmaktadır. Balıklarda 17α-ethinylestradiol, E2’ yi taklit ederek kandaki Vtg’in konsantrasyonunu artırır ve erkeklerin dişileşmesine neden olur. 17β-trenbolone (Tb) androjenik bir steroidtir ve büyük başlarda et verimini artırmak amacıyla kullanılmaktadır. Balıklarda Vtg konsantrasyonunu azalmasına neden olduğu ve dişileri erkekleştirdiği görülmüştür. Yakın bir gelecekte, dünyanın her yerinde EBk nedeniyle insanların ve doğal yaşamın üreme sistemlerinde ciddi problemler görülebilecektir

Anahtar Kelimeler

Endokrin sistem, steroid, balık, üreme

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Details

Primary Language

Turkish

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Şehriban Çek

Fatmagün Sarıhan

Publication Date

March 1, 2010

Submission Date

December 7, 2015

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-

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Year 2010 Volume: 27 Number: 1

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https://izlik.org/JA74FJ29KA

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APA

Çek, Ş., & Sarıhan, F. (2010). Endokrin Sistemi Bozan Kimyasallardan Cinsiyet Steroidlerinin Balıklardaki Etkileri. Ege Journal of Fisheries and Aquatic Sciences, 27(1), 41-46. https://izlik.org/JA74FJ29KA

Endokrin Sistemi Bozan Kimyasallardan Cinsiyet Steroidlerinin Balıklardaki Etkileri.

The Effects of Sex Steroids of Endocrine Disrupting Chemicals on Fishes.

Abstract

Keywords

Endokrin Sistemi Bozan Kimyasallardan Cinsiyet Steroidlerinin Balıklardaki Etkileri.

Öz

Anahtar Kelimeler

References

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Subjects

Journal Section

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Submission Date

Acceptance Date

Published in Issue

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Cite