Effects of Althaea officinalis supplementation on growth performance and antioxidant, stress, and immune-related gene expression in rainbow trout (Oncorhynchus mykiss)

Boran Karataş; Doğukan Kaya

doi:10.12714/egejfas.42.3.08

TR EN

Althaea officinalis katkısının gökkuşağı alabalığında (Oncorhynchus mykiss) büyüme performansı ve antioksidan, stres ve bağışıklık ile ilgili gen ekspresyonu üzerindeki etkileri

Öz

Bu çalışmada, başlangıç ortalama canlı ağırlığı 2,48 ± 0,01 g olan gökkuşağı alabalıklarında (Oncorhynchus mykiss) Althaea officinalis ekstraktının büyüme performansı, antioksidan savunma, stres ve bağışıklıkla ilişkili gen ekspresyonu üzerindeki etkilerini değerlendirmek amacıyla 42 günlük bir besleme denemesi gerçekleştirilmiştir. Bu amaçla, biri bazal kontrol diyeti (C) ve diğer ikisi farklı düzeylerde A. officinalis ekstraktı içeren (AO1: 1 g kg⁻¹, AO2: 2 g kg⁻¹) olmak üzere üç deneysel diyet formüle edilmiştir. Büyüme parametreleri, A. officinalis takviyesi yapılan gruplarda kontrol grubuna kıyasla anlamlı düzeyde artış göstermiştir (P < 0,05). Antioksidan enzimlerden süperoksit dismutaz (SOD) ve katalaz (CAT) genlerinin ekspresyon düzeyleri, takviye edilen gruplarda anlamlı şekilde yükselmiştir (P < 0,05). Ayrıca, stres ve bağışıklıkla ilişkili genler olan interlökin-1β (IL-1β), tümör nekroz faktör-alfa (TNF-α), interlökin-8 (IL-8) ve ısı şok proteini 70 (HSP-70) genlerinin ekspresyon düzeyleri de A. officinalis ekstraktı ilavesiyle anlamlı şekilde etkilenmiştir (P < 0,05). Genel olarak, bu bulgular A. officinalis ekstraktı içeren diyetlerin gökkuşağı alabalıklarında antioksidan kapasiteyi artırabileceğini, stres ve bağışıklıkla ilişkili gen ekspresyonunu düzenleyebileceğini ve sağlıklı büyümeyi destekleyebileceğini deneysel olarak ortaya koymaktadır. Bu yararlı etkiler, antioksidan ve immünomodülatör özellikleriyle bilinen A. officinalis'te bulunan flavonoidler ve fenolik bileşiklerin varlığına bağlanabilir.

Anahtar Kelimeler

Supporting Institution

This study did not receive any financial support, grant, or assistance from any public, commercial, or nonprofit funding organization.

Ethical Statement

The experiment was approved by the Local Ethics Committee for Aquatic Vertebrates at Van Yüzüncü Yıl University (Protocol No: 2025/08) and was conducted in accordance with standard ethical guidelines.

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Details

Primary Language

English

Subjects

Pisciculture

Journal Section

Research Article

Authors

Boran Karataş ^*
0000-0003-4353-1293
Türkiye

Doğukan Kaya
0000-0002-8832-5496
Türkiye

Early Pub Date

September 1, 2025

Publication Date

September 10, 2025

Submission Date

July 17, 2025

Acceptance Date

August 1, 2025

Published in Issue

Year 1970 Volume: 42 Number: 3

DOI

https://doi.org/10.12714/egejfas.42.3.08

IZ

https://izlik.org/JA56JM45JE

Cite

RIS / Bibtex

APA

Karataş, B., & Kaya, D. (2025). Effects of Althaea officinalis supplementation on growth performance and antioxidant, stress, and immune-related gene expression in rainbow trout (Oncorhynchus mykiss). Ege Journal of Fisheries and Aquatic Sciences, 42(3), 256-262. https://doi.org/10.12714/egejfas.42.3.08

Effects of Althaea officinalis supplementation on growth performance and antioxidant, stress, and immune-related gene expression in rainbow trout (Oncorhynchus mykiss)

Althaea officinalis katkısının gökkuşağı alabalığında (Oncorhynchus mykiss) büyüme performansı ve antioksidan, stres ve bağışıklık ile ilgili gen ekspresyonu üzerindeki etkileri

Öz

Anahtar Kelimeler