Are potential bisphenol-A substitutes really safe for aquatic life? Impact on primary producers

Koray Benas; Özlem Çakal Arslan

doi:10.12714/egejfas.41.3.05

TR EN

Potansiyel bisphenol-A ikameleri sucul yaşam için gerçekten güvenli mi? Birincil üreticiler üzerindeki etkisi

Öz

Bisfenol A çevre sağlığı ve insan sağlığı için tehdit oluşturmaktadır ve “Avrupa Kimyasallar Ajansı” tarafından “Çok Yüksek Önem Arz Eden Maddeler” olarak aday listeye eklenmiştir. Bu durum, bisfenol A'nın (BPA) "daha güvenli" olduğu düşünülen bisfenol analogları ile değiştirilmesine yol açmıştır. Bununla birlikte, BPA analoglarının çevre üzerindeki etkisine ilişkin çok az bilimsel çalışma bulunmaktadır. Bu çalışmada, birincil üreticileri temsil eden deniz fitoplankton türü Phaeodactylum tricornutum üzerindeki ekotoksikolojik etkilerini araştırmak için üç analog bisfenol B (BPB), bisfenol A diglisidil eter (BADGE) ve bisfenol F diglisidil eter (BFDGE) seçilmiştir. Phaeodactylum tricornutum BPB, BADGE ve BFDGE analoglarının farklı konsantrasyonlarına (0.5, 0.8, 1.0, 1.5, 2.0 mg/L) 72 saat boyunca maruz bırakılmış ve üç BPA analoğunun toksisite değerleri OECD 201 alg büyüme inhibisyonu deneyi (IC50/EC50) ile hesaplanmıştır. Elde edilen veriler ışığında, deniz fitoplanktonu Phaeodactylum tricornutum için alg büyüme inhibisyonu (IC50/EC50) değerleri 3.91 mg-BPA/L, 7.83 mg-BPB/L, 5.69 mg-BFDGE/L, 11.71 mg-BADGE/L olarak belirlenmiştir. Sonuçlar BPB, BFDGE ve BADGE'nin Phaeodactylum tricornutum için BPA alg büyüme inhibisyonuna (3.91 mg-BPA/L) kıyasla daha düşük toksisite gösterdiğini ortaya koymuştur. Bu nedenle, BPA analoglarının sucul organizmalar üzerindeki olumsuz etkilerinin sonuçlarının paylaşılması ve ekotoksikolojik risk değerlendirmelerinin yapılması gerekmektedir.

Anahtar Kelimeler

Are potential bisphenol-A substitutes really safe for aquatic life? Impact on primary producers

Abstract

Bisphenol A threat to environmental health and human health and has been added to the Candidate List as Very High Concern Substances by the European Chemicals Agency. This led to the replacement of bisphenol A (BPA) with bisphenol analogues, which were considered "safer". However, there are very few scientific studies on the impact of BPA analogues on the environment. In this study, three analogues bisphenol B (BPB), bisphenol A diglycidyl ether (BADGE) and bisphenol F diglycidyl ether (BFDGE) were selected to investigate their ecotoxicological effects on the marine phytoplankton species Phaeodactylum tricornutum, which is representative of primary producers. Phaeodactylum tricornutum was exposed to different concentrations (0.5, 0.8, 1.0, 1.5, 2.0 mg/L) of BPB, BADGE and BFDGE analogues for 72 hours and the toxicity values of three BPA analogues were calculated by OECD 201 algal growth inhibition assay (IC50/EC50). In the light of the data obtained, algal growth inhibition (IC50/EC50) values for marine phytoplankton Phaeodactylum tricornutum were determined as 3.91 mg-BPA/L, 7.83 mg-BPB/L, 5.69 mg-BFDGE/L, 11.71 mg-BADGE/L. The results revealed that BPB, BFDGE and BADGE showed lower toxicity to Phaeodactylum tricornutum compared to BPA algal growth inhibition (3.91 mg-BPA/L). Therefore, it is necessary to share the results of the adverse effects of BPA analogues on aquatic organisms and to conduct ecotoxicological risk assessments.

Keywords

Destekleyen Kurum

TUBITAK, Project no:119Y246

Proje Numarası

TUBITAK, Project no:119Y246

Etik Beyan

No specific ethical approval was necessary for the study.

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Çevre Yönetimi (Diğer)

Bölüm

Araştırma Makalesi

Yazarlar

Koray Benas ^*
0000-0002-7626-5596
Türkiye

Özlem Çakal Arslan
0000-0001-7777-3886
Türkiye

Erken Görünüm Tarihi

2 Eylül 2024

Yayımlanma Tarihi

15 Eylül 2024

Gönderilme Tarihi

29 Mayıs 2024

Kabul Tarihi

26 Ağustos 2024

Yayımlandığı Sayı

Yıl 2024 Cilt: 41 Sayı: 3

DOI

https://doi.org/10.12714/egejfas.41.3.05

IZ

https://izlik.org/JA96AC95KD

Kaynak Göster

RIS / Bibtex

APA

Benas, K., & Çakal Arslan, Ö. (2024). Are potential bisphenol-A substitutes really safe for aquatic life? Impact on primary producers. Ege Journal of Fisheries and Aquatic Sciences, 41(3), 207-212. https://doi.org/10.12714/egejfas.41.3.05