Anticancer secondary metabolites from marine sponges

Belma Konuklugil; İbrahim Seyda Uras

doi:10.12714/egejfas.38.1.12

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Anticancer secondary metabolites from marine sponges

Abstract

The oceans cover 70% of the Earth’s surface. The marine environment is an important source of secondary metabolites with high biodiversity. Besides other marine species, sponges with a wide range of secondary metabolites are an important potential for drug discovery. Cancer is one of the leading causes of death with high morbidity and mortality. It is very important to discover new therapeutic agents in the treatment of cancer. In recent years, studies on exploring new anticancer compounds are focused on the marine source. In this review, our target is collecting the studies about marine sponges secondary metabolites which have an anticancer effect. Among most of the isolated compounds from sponges and their semisynthetic derivatives, there are three FDA (US Food and Drug Administration) approved compounds and three compounds in clinical phase. Moreover, more than 40 compounds isolated from marine sponges have been tested for anticancer activity in recent 10 years. In conclusion marine sponges secondary metabolites are a promising and important source of the anticancer compounds.

Keywords

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Hidrobiyoloji

Bölüm

Kısa Bildiri

Yazarlar

Belma Konuklugil
0000-0002-4753-0450
Türkiye

İbrahim Seyda Uras ^*
0000-0001-5945-8743
Türkiye

Yayımlanma Tarihi

15 Mart 2021

Gönderilme Tarihi

25 Ocak 2020

Kabul Tarihi

31 Ocak 2020

Yayımlandığı Sayı

Yıl 2021 Cilt: 38 Sayı: 1

DOI

https://doi.org/10.12714/egejfas.38.1.12

IZ

https://izlik.org/JA29ZE62RW

Kaynak Göster

RIS / Bibtex

APA

Konuklugil, B., & Uras, İ. S. (2021). Anticancer secondary metabolites from marine sponges. Ege Journal of Fisheries and Aquatic Sciences, 38(1), 101-106. https://doi.org/10.12714/egejfas.38.1.12

Cited By

Biomedical Potential of Bioactive Compounds from Sponges of the Persian Gulf: A Systematic Review

Advances in Applied NanoBio-Technologies

https://doi.org/10.18502/aanbt.v5i4.17958

Anticancer secondary metabolites from marine sponges

Deniz süngerlerinden antikanser metabolitler

Öz

Anticancer secondary metabolites from marine sponges

Abstract

Keywords

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

Kaynak Göster

Cited By

Biomedical Potential of Bioactive Compounds from Sponges of the Persian Gulf: A Systematic Review