Anticancer secondary metabolites from marine sponges

Belma Konuklugil; İbrahim Seyda Uras

doi:10.12714/egejfas.38.1.12

TR EN

Anticancer secondary metabolites from marine sponges

Abstract

The oceans cover 70% of the Earth’s surface. The marine environment is an important source of secondary metabolites with high biodiversity. Besides other marine species, sponges with a wide range of secondary metabolites are an important potential for drug discovery. Cancer is one of the leading causes of death with high morbidity and mortality. It is very important to discover new therapeutic agents in the treatment of cancer. In recent years, studies on exploring new anticancer compounds are focused on the marine source. In this review, our target is collecting the studies about marine sponges secondary metabolites which have an anticancer effect. Among most of the isolated compounds from sponges and their semisynthetic derivatives, there are three FDA (US Food and Drug Administration) approved compounds and three compounds in clinical phase. Moreover, more than 40 compounds isolated from marine sponges have been tested for anticancer activity in recent 10 years. In conclusion marine sponges secondary metabolites are a promising and important source of the anticancer compounds.

Keywords

References

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Details

Primary Language

English

Subjects

Hydrobiology

Journal Section

Short Communication

Authors

Belma Konuklugil
0000-0002-4753-0450
Türkiye

İbrahim Seyda Uras ^*
0000-0001-5945-8743
Türkiye

Publication Date

March 15, 2021

Submission Date

January 25, 2020

Acceptance Date

January 31, 2020

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Year 2021 Volume: 38 Number: 1

DOI

https://doi.org/10.12714/egejfas.38.1.12

IZ

https://izlik.org/JA29ZE62RW

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RIS / Bibtex

APA

Konuklugil, B., & Uras, İ. S. (2021). Anticancer secondary metabolites from marine sponges. Ege Journal of Fisheries and Aquatic Sciences, 38(1), 101-106. https://doi.org/10.12714/egejfas.38.1.12

Cited By

Biomedical Potential of Bioactive Compounds from Sponges of the Persian Gulf: A Systematic Review

Advances in Applied NanoBio-Technologies

https://doi.org/10.18502/aanbt.v5i4.17958

Anticancer secondary metabolites from marine sponges

Deniz süngerlerinden antikanser metabolitler

Öz

Anticancer secondary metabolites from marine sponges

Abstract

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References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite

Cited By

Biomedical Potential of Bioactive Compounds from Sponges of the Persian Gulf: A Systematic Review