Some oxidative stress parameters in heart tissue of Zebrafish (Danio reiro) caused by mancozeb

Figen Esin Kayhan; Güllü Kaymak; Harika Eylül Esmer Duruel; Şeyma Kızılkaya

doi:10.12714/egejfas.36.4.02

TR EN

Zebrabalığı (Danio reiro) kalp dokusunda mancozeb’in neden olduğu bazı oksidatif stres parametreleri

Öz

Bu çalışmada, zebra balığı kalp dokusunda mancozeb’in bazı antioksidan enzimler üzerindeki potansiyel toksik etkileri araştırılmıştır. Zebra balığı grupları, 120 saat boyunca farklı dozlarda mancozeb (Grup A: 5 mg L^-1 ve Grup B: 7,5 mg L^-1) maruz bırakıldı. Bu çalışmada, katalaz (CAT) aktivitesi, malondialdehit (MDA) ve total protein (TP) seviyeleri spektrofotometre ile belirlenmiştir. Elde ettiğimiz sonuçlar CAT aktivitesinin ve MDA seviyesinin tüm deney gruplarında azaldığını gösterdi. Bu çalışmada CAT aktivitesi A grubunda 2,541±0,771 mg L^-1, B grubunda ise 2,011±0,201 mg L-¹ olarak bulunmuştur. CAT ve MDA aktiviteleri tüm deney gruplarında kontrol grubuna göre azalmıştır. MDA seviyeleri A grubunda 0,025±0,003 mg L^-1 ve B grubunda 0,025±0,003 mg L^-1 olarak bulunmuştur. TP seviyeleri A grubunda 9,75±1,51 mg L^-1, B grubunda ise 10,18±0,32 mg L^-1 olarak bulunmuştur. Deney grubunda TP düzeyi kontrol grubuna göre artmıştır. CAT aktivitesi ve MDA seviyelerindeki değişikliklerin deney süresine ve mancozeb dozuna bağlı olduğu belirlenmiştir. Sonuç olarak; mancozeb zebra balığı ve diğer sucul organizmalar için oldukça toksik bir maddedir.

Anahtar Kelimeler

Mancozeb,oksidatif stres,katalaz,malondialdehit,zebra balığı

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

Araştırma Makalesi

Yazarlar

Figen Esin Kayhan ^*
0000-0001-7754-1356
Türkiye

Güllü Kaymak
0000-0001-6309-0208
Türkiye

Harika Eylül Esmer Duruel
0000-0002-0792-2062

Şeyma Kızılkaya
0000-0001-8065-217X
Türkiye

Yayımlanma Tarihi

15 Aralık 2019

Gönderilme Tarihi

5 Şubat 2019

Kabul Tarihi

2 Temmuz 2019

Yayımlandığı Sayı

Yıl 1970 Cilt: 36 Sayı: 4

DOI

https://doi.org/10.12714/egejfas.36.4.02

IZ

https://izlik.org/JA25AU96UC

Kaynak Göster

RIS / Bibtex

APA

Kayhan, F. E., Kaymak, G., Esmer Duruel, H. E., & Kızılkaya, Ş. (2019). Some oxidative stress parameters in heart tissue of Zebrafish (Danio reiro) caused by mancozeb. Ege Journal of Fisheries and Aquatic Sciences, 36(4), 325-328. https://doi.org/10.12714/egejfas.36.4.02

Zebrabalığı (Danio reiro) kalp dokusunda mancozeb’in neden olduğu bazı oksidatif stres parametreleri

Zebrabalığı (Danio reiro) kalp dokusunda mancozeb’in neden olduğu bazı oksidatif stres parametreleri

Öz

Anahtar Kelimeler