Year 2016, Volume 33 , Issue 2, Pages 113 - 120 2016-05-15

Alireza Mirvaghefi* • Mohsen Ali • Hadi Poorbagher
Effects of vitamin C on oxidative stress parameters in rainbow trout exposed to diazinon

Alireza MİRVAGHEFİ [1] , Mohsen ALİ [2] , Hadi POORBAGHER [3]


Abstract: : Diazinon (Organophosphorus insecticide) can cause reactive oxidative stresses during metabolism of aquatic organisms. The study presented here aimed to investigate the antioxidant effect of vitamin C on antioxidant enzyme activities and lipid peroxidation in rainbow trout exposed to subchronic dosage diazinon. A total number of 360 Oncorhynchus mykiss were allocated into four treatment groups (with three replicates): control; diazinon (0.1 mg L 1); vitamin C (300 mg kg 1 in diet) plus diazinon (0.1 mg L-1), and vitamin C (1000 mg kg-1 in diet) plus diazinon (0.1 mg L-1). After two and four weeks, blood samples were collected and superoxide dismutase, catalase enzymes, total antioxidant capacity and malondialdehyte index were measured. The specimens exposed exclusively to diazinon showed a significant decrease in superoxide dismutase and total antioxidant capacity activities and also an increase in catalase activity and malondialdehyde index compared to those of the control group. The changes in oxidative stress parameters may be related to destructive free oxiradicals such as superoxide and hydroxyl radicals produced in diazinon metabolism. In conclusion, vitamin C moderated activity of the antioxidant enzyme, increased the total antioxidant capacity, and decreased cellular damages caused by destructive lipid peroxidation process in presence of diazinon.

Keywords: Diazinon, antioxidant, vitamin C, enzyme, malondialdehyde, catalase
Diazinon, antioxidant, vitamin C, enzyme, malondialdehyde, catalase
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Journal Section Articles
Authors

Author: Alireza MİRVAGHEFİ

Author: Mohsen ALİ

Author: Hadi POORBAGHER

Dates

Application Date : May 15, 2016
Acceptance Date : July 6, 2020
Publication Date : May 15, 2016

APA Mi̇rvaghefi̇, A , Ali̇, M , Poorbagher, H . (2016). Effects of vitamin C on oxidative stress parameters in rainbow trout exposed to diazinon. Ege Journal of Fisheries and Aquatic Sciences , 33 (2) , 113-120 . DOI: 10.12714/egejfas.2016.33.2.04