Araştırma Makalesi
Yıl 2022,
Cilt: 2 Sayı: 1, 16 - 24, 25.01.2022
Öz
Kaynakça
- 1. Lebel M, Ciprofloxacin: chemistry, mechanism of action, resistance, antimicrobial spectrum, pharmacokinetics, clinical trials, and adverse reactions, Pharmacotherapy 1988; 8: 3-33.
- 2. S.O. Kayaalp, Tibbi Farmakoloji,801,Feryal Matbaacılık San.Tic.,Ankara (1991).
- 3. Fratini L, Schapoval EES, Ciprofloxacin determination by visible light spectrophotometry using iron(III)nitrate, Int. J Pharm. 1996; 127(2): 279-282.
- 4. Vance-Bryan K, Guay DR, Rotschafer JC, Clinical pharmacokinetics of ciprofloxacin, Clin. Pharmacokinet, 1990; 19(6): 434-461.
- 5. Akkan AG, Mutlu I, Özyazgan A, Gök A, Yiğit A, Ozuner Z, Senses V, Pekel H, Comparative tear concentrations of topical y applied ciprofloxacin, ofloxacin, and norfloxacin in human eyes, Int. J Clin. Pharm. Therap. 1997; 35: 214-217.
- 6. Navalon A, Ballesteros O, Blanc R, Vilchez JL, Determination of ciprofloxacin in human urine and serum samples by solid-phase spectrofluorimetry, Talanta 2000; 52: 845-852.
- 7. Oliphant CM, Green GM, Quinolones: A Comprehensive Review, Clin. Pharmacol. 2002; 65(3): 455-464.
- 8. Hasan N, Siddiqui FA, Sher N, Shafi N, Zubair A, Afzal M, Development and validation of a Reverse Phase HPLC method for the analysis of ciprofloxacin and its application in bulk and different dosage formulations, World Appl. Sci. J. 2014; 31(5): 730-740.
- 9. Mostafa S, El-Sadek M, Alla EA, Spectrophotometric determination of ciprofloxacin, enrofloxacin and pefloxacin through charge transfer complex formation, J Pharm. Biomed. Analy. 2002; 27: 133-142.
- 10. Akyüz BG, Ozkorucuklu SP, Kır E, Bastemur GY, Determination of ciprofloxacin In pharmaceutical dosage, human serum and urine, using molecularly ımprinted polymer modified electrode by voltammetry, Eur. J Sci. Technol. 2020; 20: 859-865.
- 11. Basavaiah K, Nagegowda P, Somashekar CB, Ramakrishna V, Spectrophotometric and Titrimetric Determination of Ciprofloxacin Based on Reaction with Cerium (IV) Sulphate, Science Asia, 2006; 32: 403-409.
- 12. Nagaralli BS, Jaldappagari S, Melwanki MB, Sensitive spectrophotometric methods for the determination of amoxycillin, ciprofloxacin and piroxicam in pure and pharmaceutical formulations, J Pharm. Biomed. Analy. 2002; 29: 859-864.
- 13. Chowdary KPR, Prasad YVR, A new spectrophotometric method for the determination of fluoroquinolone in dosage forms and in dissolution rate studies. Indian Drugs, 1994; 31: 277-279.
- 14. El-Brashy AM, Metwall ME, El-Sepai FA, Spectrophotometric determination of some fluoroquinolone antibacterials through charge-transfer and ıon-pair complexation reactions, Bull. Korean Chem. Soc. 2004; 25(3): 365-372.
- 15. Zareh MM, Saad MZ, Hassan WS, Elhennaw ME, Sebaiy MM, Validation of spectrophotometric method for determination of esomeprazole and ciprofloxacine in their püre and dosage forms, Int. J. Pahrm. Sci. Dev. Res. 2020; 6(1): 1-5.
- 16. Edith CLC, Hérida RNS, Spectrophotometric determination of ciprofloxacin hydrochloride in ophthalmic solution, Adv. Anal. Chem. 2012; 2: 74-79.
- 17. Braggio S, Barnaby RJ, Grossi P, Cugola M. A strategy for validation of bioanalytical methods, J Pharm. Biomed. Anal. 1996; 14(4): 375-88.
- 18. Validation of Analytical Procedures, Proceedings of the International Conference on Harmonisation (ICH). Commision of the European Communities, 1996.
Determination Of Ciprofloxacin With Zero-, First- And SecondOrder Derivative Spectrophotometric Method In Water And Methanol Media
Öz
Ciprofloxacin is a synthetic fluoroquinolone derivative antibiotic used to treat various bacterial infections. Simple, fast and reliable zero-, first- and second-order derivative spectrophotometric methods were developed for determination of ciprofloxacin in two pharmaceutical dosage forms. The solutions of standard and the sample were prepared in methanol and water medium. The quantitative determination of the drug was carried out using the zero-, first- and second-order derivative values measured 270-310 nm (N=6) Calibration graphs constructed at their wavelengths of determination were linear in concentration range of ciprofloxacin using peak to zero 2.00-10.00 m/mL for zero-, firstand second-order derivative spectrophotometric method. The developed methods were successfully applied for the assay of pharmaceutical dosage forms for two solvent media which do not require any preliminary separation or treatment of the samples. The details of statistical treatment of analytical data are also presented (p>0.05).
Anahtar Kelimeler
Ciprofloxacin derivative spectrophotometric method different media
Kaynakça
- 1. Lebel M, Ciprofloxacin: chemistry, mechanism of action, resistance, antimicrobial spectrum, pharmacokinetics, clinical trials, and adverse reactions, Pharmacotherapy 1988; 8: 3-33.
- 2. S.O. Kayaalp, Tibbi Farmakoloji,801,Feryal Matbaacılık San.Tic.,Ankara (1991).
- 3. Fratini L, Schapoval EES, Ciprofloxacin determination by visible light spectrophotometry using iron(III)nitrate, Int. J Pharm. 1996; 127(2): 279-282.
- 4. Vance-Bryan K, Guay DR, Rotschafer JC, Clinical pharmacokinetics of ciprofloxacin, Clin. Pharmacokinet, 1990; 19(6): 434-461.
- 5. Akkan AG, Mutlu I, Özyazgan A, Gök A, Yiğit A, Ozuner Z, Senses V, Pekel H, Comparative tear concentrations of topical y applied ciprofloxacin, ofloxacin, and norfloxacin in human eyes, Int. J Clin. Pharm. Therap. 1997; 35: 214-217.
- 6. Navalon A, Ballesteros O, Blanc R, Vilchez JL, Determination of ciprofloxacin in human urine and serum samples by solid-phase spectrofluorimetry, Talanta 2000; 52: 845-852.
- 7. Oliphant CM, Green GM, Quinolones: A Comprehensive Review, Clin. Pharmacol. 2002; 65(3): 455-464.
- 8. Hasan N, Siddiqui FA, Sher N, Shafi N, Zubair A, Afzal M, Development and validation of a Reverse Phase HPLC method for the analysis of ciprofloxacin and its application in bulk and different dosage formulations, World Appl. Sci. J. 2014; 31(5): 730-740.
- 9. Mostafa S, El-Sadek M, Alla EA, Spectrophotometric determination of ciprofloxacin, enrofloxacin and pefloxacin through charge transfer complex formation, J Pharm. Biomed. Analy. 2002; 27: 133-142.
- 10. Akyüz BG, Ozkorucuklu SP, Kır E, Bastemur GY, Determination of ciprofloxacin In pharmaceutical dosage, human serum and urine, using molecularly ımprinted polymer modified electrode by voltammetry, Eur. J Sci. Technol. 2020; 20: 859-865.
- 11. Basavaiah K, Nagegowda P, Somashekar CB, Ramakrishna V, Spectrophotometric and Titrimetric Determination of Ciprofloxacin Based on Reaction with Cerium (IV) Sulphate, Science Asia, 2006; 32: 403-409.
- 12. Nagaralli BS, Jaldappagari S, Melwanki MB, Sensitive spectrophotometric methods for the determination of amoxycillin, ciprofloxacin and piroxicam in pure and pharmaceutical formulations, J Pharm. Biomed. Analy. 2002; 29: 859-864.
- 13. Chowdary KPR, Prasad YVR, A new spectrophotometric method for the determination of fluoroquinolone in dosage forms and in dissolution rate studies. Indian Drugs, 1994; 31: 277-279.
- 14. El-Brashy AM, Metwall ME, El-Sepai FA, Spectrophotometric determination of some fluoroquinolone antibacterials through charge-transfer and ıon-pair complexation reactions, Bull. Korean Chem. Soc. 2004; 25(3): 365-372.
- 15. Zareh MM, Saad MZ, Hassan WS, Elhennaw ME, Sebaiy MM, Validation of spectrophotometric method for determination of esomeprazole and ciprofloxacine in their püre and dosage forms, Int. J. Pahrm. Sci. Dev. Res. 2020; 6(1): 1-5.
- 16. Edith CLC, Hérida RNS, Spectrophotometric determination of ciprofloxacin hydrochloride in ophthalmic solution, Adv. Anal. Chem. 2012; 2: 74-79.
- 17. Braggio S, Barnaby RJ, Grossi P, Cugola M. A strategy for validation of bioanalytical methods, J Pharm. Biomed. Anal. 1996; 14(4): 375-88.
- 18. Validation of Analytical Procedures, Proceedings of the International Conference on Harmonisation (ICH). Commision of the European Communities, 1996.
Toplam 18 adet kaynakça vardır.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Eczacılık ve İlaç Bilimleri |
| Bölüm | Research Articles |
| Yazarlar | |
| Yayımlanma Tarihi | 25 Ocak 2022 |
| Yayımlandığı Sayı | Yıl 2022 Cilt: 2 Sayı: 1 |
