In this research, the identification of cell components by FT-IR (Fourier Transform Infrared) and ESBL production of Enterobacteriaceae strains isolated from inpatients in Kilis state hospital were studied. Cell components of isolates were detected by using FTIR spectroscopy (4000-400 cm-1). ESBL production of strains was investigated with the cefepime-clavulanic acid, cefotetan-cloxacillin, cefotaxime-clavulanic acid and ceftazidime-clavulanic acid E-strip. According to the E-strip results, it can be stated that only five isolates of Enteric strain were able to produce ESBL. Cefotetan/cefotetan+cloxacillin ratio was determined to be ≥8 µg/mL for Salmonella spp. This ratio was indicated that Salmonella spp. produced C group beta lactamase in Ambler classificataion. Our FTIR analysis revealed that FTIR spectroscopy can be routinely used in the investigation of cell components although it is an unsuccessful method for diagnosis of closely-related species.
Extended-spectrum β-lactamase (ESBL) FTIR Enterobacteriaceae
Genişlemiş spektrumlu beta-laktamaz (GSBL) FTIR Enterobacteriaceae
Birincil Dil | Türkçe |
---|---|
Konular | Yapısal Biyoloji |
Bölüm | ARAŞTIRMA MAKALESİ (Research Article) |
Yazarlar | |
Yayımlanma Tarihi | 31 Ekim 2020 |
Gönderilme Tarihi | 6 Şubat 2020 |
Kabul Tarihi | 17 Nisan 2020 |
Yayımlandığı Sayı | Yıl 2020Cilt: 23 Sayı: 5 |
2022-JIF = 0.500
2022-JCI = 0.170
Uluslararası Hakemli Dergi (International
Peer Reviewed Journal)
Dergimiz, herhangi bir başvuru veya yayımlama ücreti almamaktadır. (Free submission and publication)
Yılda 6 sayı yayınlanır. (Published 6 times a year)
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