Comparison of Antioxidant Activities of Mono-, Di- and Tri-substituted Coumarins

Hülya Çelik Onar; Hasniye Yaşa; Oktay Sin

doi:10.18596/jotcsa.624265

Araştırma Makalesi

Comparison of Antioxidant Activities of Mono-, Di- and Tri-substituted Coumarins

Yıl 2020, Cilt: 7 Sayı: 1, 87 - 96, 15.02.2020

Hülya Çelik Onar Hasniye Yaşa Oktay Sin

https://doi.org/10.18596/jotcsa.624265

Cited By: 3

Öz

In this study; Numerous
coumarin compounds were synthesized by Pechmann and Knoevenagel methods, and
the substitution of the formyl group was provided by the Duff reaction. The IR
spectras and melting points of the synthesized compounds were compared with the
literature values. Also confirmed by GC/MS analysis. And the synthesized
coumarin derivatives were compared in terms of antioxidant activity according
to DPPH and Cuprac methods. The main aim of the study is to determine the
effects of substituents on antioxidant activity.

Anahtar Kelimeler

Coumarin, Pechmann reaction, Knoevenagel reaction, Duff reaction, Cuprac method, DDPH method

Destekleyen Kurum

Research Fund of The İstanbul University-Cerrahpaşa.

Proje Numarası

FYL-2017-23395.

Kaynakça

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