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Micro and Nanogels for Biomedical Applications

Yıl 2020, The 100 Year of Polymers, 407 - 424, 01.11.2020
https://doi.org/10.15671/hjbc.810599

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Micro and nano hydrogels developed from natural and synthetic polymers have garnered great deal of attention in scientific and industrial realms due to their higher surface area, degree of swelling and active material loading capacity, softness and flexibility, as well as their similarity to natural tissues. Particularly, biocompatible, non-toxic, and biodegradable micro/nano vehicles with tailor made design and functionalization facilities their use with excellent feasibility for a variety of biomedical applications such as tissue engineering, bioimaging and drug delivery. However, these platforms require rational design and functionalization strategies to cope with barriers of in vivo environment to pass into clinical use. Firstly, an ideal carrier should be biocompatible, and capable of evasion from immune elimination, specifically target at desired sites and sustainably release the therapeutic cargo in response to microenvironment conditions. Despite the few setbacks in micro/nano vehicle design and several successful formulations translated to clinical use and majority of the carries are yet to achieve complete success for all biological criteria. In this review, design, and functionalization strategies of micro and nanogels have been summarized and the recent progress in biomedical applications of microgels and nanogels have been outlined with a primary focus placed on drug and biomolecule delivery applications.

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Kaynakça

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Yıl 2020, The 100 Year of Polymers, 407 - 424, 01.11.2020
https://doi.org/10.15671/hjbc.810599

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Kaynakça

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Toplam 148 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Mühendislik
Bölüm Articles
Yazarlar

Mehmet Can Bu kişi benim 0000-0002-5993-206X

Olgun Guven Bu kişi benim 0000-0002-7559-1365

Nurettin Sahiner 0000-0003-0120-530X

Yayımlanma Tarihi 1 Kasım 2020
Kabul Tarihi 16 Ekim 2020
Yayımlandığı Sayı Yıl 2020 The 100 Year of Polymers

Kaynak Göster

APA Can, M., Guven, O., & Sahiner, N. (2020). Micro and Nanogels for Biomedical Applications. Hacettepe Journal of Biology and Chemistry, 48(5), 407-424. https://doi.org/10.15671/hjbc.810599
AMA Can M, Guven O, Sahiner N. Micro and Nanogels for Biomedical Applications. HJBC. Kasım 2020;48(5):407-424. doi:10.15671/hjbc.810599
Chicago Can, Mehmet, Olgun Guven, ve Nurettin Sahiner. “Micro and Nanogels for Biomedical Applications”. Hacettepe Journal of Biology and Chemistry 48, sy. 5 (Kasım 2020): 407-24. https://doi.org/10.15671/hjbc.810599.
EndNote Can M, Guven O, Sahiner N (01 Kasım 2020) Micro and Nanogels for Biomedical Applications. Hacettepe Journal of Biology and Chemistry 48 5 407–424.
IEEE M. Can, O. Guven, ve N. Sahiner, “Micro and Nanogels for Biomedical Applications”, HJBC, c. 48, sy. 5, ss. 407–424, 2020, doi: 10.15671/hjbc.810599.
ISNAD Can, Mehmet vd. “Micro and Nanogels for Biomedical Applications”. Hacettepe Journal of Biology and Chemistry 48/5 (Kasım 2020), 407-424. https://doi.org/10.15671/hjbc.810599.
JAMA Can M, Guven O, Sahiner N. Micro and Nanogels for Biomedical Applications. HJBC. 2020;48:407–424.
MLA Can, Mehmet vd. “Micro and Nanogels for Biomedical Applications”. Hacettepe Journal of Biology and Chemistry, c. 48, sy. 5, 2020, ss. 407-24, doi:10.15671/hjbc.810599.
Vancouver Can M, Guven O, Sahiner N. Micro and Nanogels for Biomedical Applications. HJBC. 2020;48(5):407-24.

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