Araştırma Makalesi
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Seropositivity of Mycobacterium paratuberculosis in Cattle with Chronic Diarrhea in the Middle Black Sea Region

Yıl 2018, Cilt: 13 Sayı: 1, 1 - 5, 25.04.2018
https://doi.org/10.17094/ataunivbd.297128

Öz

Paratuberculosis (Johne's disease), caused by Mycobacterium avium subsp. paratuberculosis (MAP) is one of the most common and contagious infections of farm animals mainly cattle herds. MAP leads to a chronic and progressive enteric disease that results poor body condition, reduced milk production, premature culling, and decimate slaughter value in cattle industry. The aim of this study was to investigate of the seropositivity of MAP in cattle with chronic diarrhea in Middle Black Sea Region. For this purpose, a total of 859 Holstein-Friesian dairy cattle (˃2 years old) from 15 herds with companied to chronic diarrhea were examined in Amasya and Samsun provinces, between 2012 and 2014. MAP antibodies were determined by indirect commercial enzyme-linked immunosorbent assay ELISA (iELISA) kit. Of the 859 samples, 86 (10.0%) and of 15 herds, 7 (46.7%) were positive for the MAP antibodies. In 2012, 2013 and 2014, positive rates of 2.4%, 21.5% and 50% were detected, respectively. As a result, there was a significant increase in MAP seropositivity in chronic diarrheal cattle. It is thought that the results of the study will contribute to the development of effective control programs for eradication of the disease and clinicians working in the region will benefit from the attention of veterinarians.

Kaynakça

  • 1. Nielsen SS., Toft N., 2009. A review of prevalences of paratuberculosis in farmed animals in Europe. Prev Vet Med, 88, 1-14.
  • 2. Cho J., Tauer LW., Schukken YH., Gomez MI., Smith RL., Lu Z., Grohn YT., 2012. Economic analysis of Mycobacterium avium subspecies paratuberculosis vaccines in dairy herds. J Dairy Sci, 95, 1855-1872.
  • 3. Fernández-Silva JA., Correa-Valencia NM., Ramírez NF., 2014. Systematic review of the prevalence of paratuberculosis in cattle, sheep, and goats in Latin America and the Caribbean. Trop. Anim. Health. Prod, 46, 1321-1340.
  • 4. Makav M., Gokce E., 2013. Seroprevalence of subclinical paratuberculosis in cattle in Kars Region. Kafkas Üniv Vet Fak Derg, 19, 913-916.
  • 5. Yildirim D., Civelek T., 2013. Prevalence of subclinical paratuberculosis in dairy cattle in Usak region. Kafkas Üniv Vet Fak Derg, 19, 121-126.
  • 6. Buyuk F., Celebi O., Akca D., Otlu S., Tazegu E., Gulmez A., Sahin M., 2014. Estimated apparent and true prevalence of paratuberculosis in sheep herds of the Kars Region in Northeastern Turkey. Vet Med, 59, 331-335.
  • 7. Dieguez FJ., Gonzalez AM., Menendez S., Vilar MJ., Sanjuan ML., Yus E., Arnaiz I., 2009. Evaluation of four commercial serum ELISAs for detection of Mycobacterium avium subsp. paratuberculosis infection in dairy cows. Vet J, 180, 231-235.
  • 8. Gupta A., Rani SM., Agrawal P., Gupta PK., 2012. Seroprevalence of paratuberculosis (Johne’s disease) in cattle population of South-Western Bangalore using ELISA kit. J Vet Med, 2, 196-200.
  • 9. Donat K., Schlotter K., Erhardt G., Brandt HR., 2014. Prevalence of paratuberculosis in cattle and control measures within the herd influence the performance of ELISA tests. Vet Rec, 174, 119.
  • 10. Böttcher J., Gangl A., 2004. Mycobacterium avium ssp. paratuberculosis combined serological testing and classification of individual animals and herds. J Vet Med B, 51, 443-448.
  • 11. Tiwari A., VanLeeuwen JA., Dohoo IR., Keefe GP., Haddad JP., Scott HM., Whiting T., 2009. Risk factors associated with Mycobacterium avium subspecies paratuberculosis seropositivity in Canadian dairy cows and herds. Prev Vet Med, 88, 32-41.
  • 12. Losinger WC., 2006. Economic impacts of reduced milk production associated with epidemiological risk factors for Johne’s disease on dairy operations in the USA. J Dairy Res, 73, 33-43.
  • 13. Boelaert F., Walravens K., Biront P., Vermeersch JP., Berkvens D., Godfroid J., 2000. Prevalence of paratuberculosis (Johne’s disease) in the Belgian cattle population. Vet Microbiol, 77, 269-281.
  • 14. Sechi P., Paolotto P., McCrindle CME., Cenci-Goga BT., 2013. Seroepidemiological study of Johne’s-disease in dairy cattle in Umbria, Italy. Italian J Anim Sci, 12, 196-199.
  • 15. Good M., Clegg T., Sheridan H., Yearsely D., O’Brien T., Egan J., Mullowney P., 2009. Prevalence and distribution of paratuberculosis (Johne’s disease) in cattle herds in Ireland. Irish Vet J, 62, 597-606.
  • 16. Muskens J., Barkema H.W., Russchen E., Van Maanen K., Schukken YH., Bakker B. 2000. Prevalence and regional distribution of paratuberculosis in dairy herds in The Netherlands. Vet Microbiol, 77, 253-261.
  • 17. Cetinkaya B., Erdogan HM., Morgan KL., 1998. Prevalence, incidence and geographical distribution of Johne’s disease in cattle in England and the Welsh borders. Vet Rec, 143, 265-269.
  • 18. Atala N., Akcay E., 2001. Türkiye genelinde sığır paratüberkülozu prevalansının ELISA ile araştırılması (in Turkish with English abstract). Etlik Vet Mikrob Derg, 12, 39-48.
  • 19. Vural B., Atala N. 1988. Serological study on bovine paratuberculosis in central Anatolia using the microcomplement fixation and tube complement fixation tests. Etlik Vet Mikrob Derg, 6, 87-97.
  • 20. Ozturk D., Pehlivanoglu F., Tok A., Gunlu S., Guldali Y., Turutoglu H., 2010. Seroprevalence of paratuberculosis in the Burdur province (Turkey), in dairy cattle using the enzyme linked ımmunosorbent assay (ELISA). Israel J Vet Med, 65, 53-57.

Orta Karadeniz Bölgesinde Kronik İshalli Sığırlarda Mycobacterium paratuberculosis’in Seropozitifliği

Yıl 2018, Cilt: 13 Sayı: 1, 1 - 5, 25.04.2018
https://doi.org/10.17094/ataunivbd.297128

Öz

Paratüberküloz (Johne’s hastalığı), Mycobacterium avium subsp. paratuberculosis (MAP) tarafından oluşturulan, başta sığır sürüleri olmak üzere çiftlik hayvanlarının en yaygın ve bulaşıcı enfeksiyonlarından birisidir. MAP sığırlarda kronik ve ilerleyici bir enterik hastalığa neden olarak vücut kondüsyon kaybı, düşük süt verimi, erken kesim ve düşük kesim değerine neden olan bir hastalıktır. Bu çalışmada, orta Karadeniz bölgesindeki kronik ishalli şikayeti olan sığırlarda MAP antikor prevalansının tespiti amaçlandı. Bu amaçla 2012-2014 yılları arasında Amasya ve Samsun illerindeki 15 işletmeden 2 yaş ve üzeri kronik ishalli 859 Holstein-Friesian süt sığırı incelendi. MAP antikorları ticari bir indirekt ELISA kiti (iELISA) ile belirlendi. İncelenen serum örneklerinin 86’sı (%10,0) ve işletmelerin 7’si (%46,7) MAP antikorları yönünden pozitif olarak bulundu. 2012, 2013 ve 2014 yıllarında sırasıyla %2,4, %21,5 ve %50,0 oranında pozitiflik saptandı. Sonuç olarak, kronik ishalli sığırlarda MAP seropozitifliği bakımından belirgin bir artış olduğu görüldü. Çalışma sonuçlarının bölgede görev yapan klinisyen veteriner hekimlerin dikkatini çekmek açısından faydalı olacağı ve hastalığın eredikasyonu için etkin kontrol programlarının geliştirilmesi yönünde önemli katkılar yapacağı düşünülmektedir.



 

Kaynakça

  • 1. Nielsen SS., Toft N., 2009. A review of prevalences of paratuberculosis in farmed animals in Europe. Prev Vet Med, 88, 1-14.
  • 2. Cho J., Tauer LW., Schukken YH., Gomez MI., Smith RL., Lu Z., Grohn YT., 2012. Economic analysis of Mycobacterium avium subspecies paratuberculosis vaccines in dairy herds. J Dairy Sci, 95, 1855-1872.
  • 3. Fernández-Silva JA., Correa-Valencia NM., Ramírez NF., 2014. Systematic review of the prevalence of paratuberculosis in cattle, sheep, and goats in Latin America and the Caribbean. Trop. Anim. Health. Prod, 46, 1321-1340.
  • 4. Makav M., Gokce E., 2013. Seroprevalence of subclinical paratuberculosis in cattle in Kars Region. Kafkas Üniv Vet Fak Derg, 19, 913-916.
  • 5. Yildirim D., Civelek T., 2013. Prevalence of subclinical paratuberculosis in dairy cattle in Usak region. Kafkas Üniv Vet Fak Derg, 19, 121-126.
  • 6. Buyuk F., Celebi O., Akca D., Otlu S., Tazegu E., Gulmez A., Sahin M., 2014. Estimated apparent and true prevalence of paratuberculosis in sheep herds of the Kars Region in Northeastern Turkey. Vet Med, 59, 331-335.
  • 7. Dieguez FJ., Gonzalez AM., Menendez S., Vilar MJ., Sanjuan ML., Yus E., Arnaiz I., 2009. Evaluation of four commercial serum ELISAs for detection of Mycobacterium avium subsp. paratuberculosis infection in dairy cows. Vet J, 180, 231-235.
  • 8. Gupta A., Rani SM., Agrawal P., Gupta PK., 2012. Seroprevalence of paratuberculosis (Johne’s disease) in cattle population of South-Western Bangalore using ELISA kit. J Vet Med, 2, 196-200.
  • 9. Donat K., Schlotter K., Erhardt G., Brandt HR., 2014. Prevalence of paratuberculosis in cattle and control measures within the herd influence the performance of ELISA tests. Vet Rec, 174, 119.
  • 10. Böttcher J., Gangl A., 2004. Mycobacterium avium ssp. paratuberculosis combined serological testing and classification of individual animals and herds. J Vet Med B, 51, 443-448.
  • 11. Tiwari A., VanLeeuwen JA., Dohoo IR., Keefe GP., Haddad JP., Scott HM., Whiting T., 2009. Risk factors associated with Mycobacterium avium subspecies paratuberculosis seropositivity in Canadian dairy cows and herds. Prev Vet Med, 88, 32-41.
  • 12. Losinger WC., 2006. Economic impacts of reduced milk production associated with epidemiological risk factors for Johne’s disease on dairy operations in the USA. J Dairy Res, 73, 33-43.
  • 13. Boelaert F., Walravens K., Biront P., Vermeersch JP., Berkvens D., Godfroid J., 2000. Prevalence of paratuberculosis (Johne’s disease) in the Belgian cattle population. Vet Microbiol, 77, 269-281.
  • 14. Sechi P., Paolotto P., McCrindle CME., Cenci-Goga BT., 2013. Seroepidemiological study of Johne’s-disease in dairy cattle in Umbria, Italy. Italian J Anim Sci, 12, 196-199.
  • 15. Good M., Clegg T., Sheridan H., Yearsely D., O’Brien T., Egan J., Mullowney P., 2009. Prevalence and distribution of paratuberculosis (Johne’s disease) in cattle herds in Ireland. Irish Vet J, 62, 597-606.
  • 16. Muskens J., Barkema H.W., Russchen E., Van Maanen K., Schukken YH., Bakker B. 2000. Prevalence and regional distribution of paratuberculosis in dairy herds in The Netherlands. Vet Microbiol, 77, 253-261.
  • 17. Cetinkaya B., Erdogan HM., Morgan KL., 1998. Prevalence, incidence and geographical distribution of Johne’s disease in cattle in England and the Welsh borders. Vet Rec, 143, 265-269.
  • 18. Atala N., Akcay E., 2001. Türkiye genelinde sığır paratüberkülozu prevalansının ELISA ile araştırılması (in Turkish with English abstract). Etlik Vet Mikrob Derg, 12, 39-48.
  • 19. Vural B., Atala N. 1988. Serological study on bovine paratuberculosis in central Anatolia using the microcomplement fixation and tube complement fixation tests. Etlik Vet Mikrob Derg, 6, 87-97.
  • 20. Ozturk D., Pehlivanoglu F., Tok A., Gunlu S., Guldali Y., Turutoglu H., 2010. Seroprevalence of paratuberculosis in the Burdur province (Turkey), in dairy cattle using the enzyme linked ımmunosorbent assay (ELISA). Israel J Vet Med, 65, 53-57.
Toplam 20 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Araştırma Makaleleri
Yazarlar

Mehmet Tutuncu

Yunus Kilicoglu Bu kişi benim

Murat Güzel

Didem Pekmezci

Timur Gulhan

Yayımlanma Tarihi 25 Nisan 2018
Yayımlandığı Sayı Yıl 2018 Cilt: 13 Sayı: 1

Kaynak Göster

APA Tutuncu, M., Kilicoglu, Y., Güzel, M., Pekmezci, D., vd. (2018). Seropositivity of Mycobacterium paratuberculosis in Cattle with Chronic Diarrhea in the Middle Black Sea Region. Atatürk Üniversitesi Veteriner Bilimleri Dergisi, 13(1), 1-5. https://doi.org/10.17094/ataunivbd.297128
AMA Tutuncu M, Kilicoglu Y, Güzel M, Pekmezci D, Gulhan T. Seropositivity of Mycobacterium paratuberculosis in Cattle with Chronic Diarrhea in the Middle Black Sea Region. Atatürk Üniversitesi Veteriner Bilimleri Dergisi. Nisan 2018;13(1):1-5. doi:10.17094/ataunivbd.297128
Chicago Tutuncu, Mehmet, Yunus Kilicoglu, Murat Güzel, Didem Pekmezci, ve Timur Gulhan. “Seropositivity of Mycobacterium Paratuberculosis in Cattle With Chronic Diarrhea in the Middle Black Sea Region”. Atatürk Üniversitesi Veteriner Bilimleri Dergisi 13, sy. 1 (Nisan 2018): 1-5. https://doi.org/10.17094/ataunivbd.297128.
EndNote Tutuncu M, Kilicoglu Y, Güzel M, Pekmezci D, Gulhan T (01 Nisan 2018) Seropositivity of Mycobacterium paratuberculosis in Cattle with Chronic Diarrhea in the Middle Black Sea Region. Atatürk Üniversitesi Veteriner Bilimleri Dergisi 13 1 1–5.
IEEE M. Tutuncu, Y. Kilicoglu, M. Güzel, D. Pekmezci, ve T. Gulhan, “Seropositivity of Mycobacterium paratuberculosis in Cattle with Chronic Diarrhea in the Middle Black Sea Region”, Atatürk Üniversitesi Veteriner Bilimleri Dergisi, c. 13, sy. 1, ss. 1–5, 2018, doi: 10.17094/ataunivbd.297128.
ISNAD Tutuncu, Mehmet vd. “Seropositivity of Mycobacterium Paratuberculosis in Cattle With Chronic Diarrhea in the Middle Black Sea Region”. Atatürk Üniversitesi Veteriner Bilimleri Dergisi 13/1 (Nisan 2018), 1-5. https://doi.org/10.17094/ataunivbd.297128.
JAMA Tutuncu M, Kilicoglu Y, Güzel M, Pekmezci D, Gulhan T. Seropositivity of Mycobacterium paratuberculosis in Cattle with Chronic Diarrhea in the Middle Black Sea Region. Atatürk Üniversitesi Veteriner Bilimleri Dergisi. 2018;13:1–5.
MLA Tutuncu, Mehmet vd. “Seropositivity of Mycobacterium Paratuberculosis in Cattle With Chronic Diarrhea in the Middle Black Sea Region”. Atatürk Üniversitesi Veteriner Bilimleri Dergisi, c. 13, sy. 1, 2018, ss. 1-5, doi:10.17094/ataunivbd.297128.
Vancouver Tutuncu M, Kilicoglu Y, Güzel M, Pekmezci D, Gulhan T. Seropositivity of Mycobacterium paratuberculosis in Cattle with Chronic Diarrhea in the Middle Black Sea Region. Atatürk Üniversitesi Veteriner Bilimleri Dergisi. 2018;13(1):1-5.