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Probiotics, prebiotics and their effects on intestinal and skin health

Yıl 2021, Cilt: 16 Sayı: 64, 263 - 289, 28.11.2022

Öz

The human gut microbiota is fundamental to health and is associated with a variety of diseases. Maintaining an intact intestinal barrier plays an important role in preventing tissue injury, pathogen infection and disease development and improving gut health and overall good health. Bacterial translocation can occur when the intestinal barrier function is compromised. Probiotics are live microorganisms that are ingested to promote health. The benefits of probiotics are based on their effects on the intestinal microbiota. There have been multiple studies about the role of probiotics in improving health by treating gastrointestinal, liver and pancreatic disease, atopic dermatitis (AD) and preventing infection. Probiotics like lactic acid and bifidobacterium are widely produced in the food industry and customer demand for these substances is continuously increasing. Prebiotics are non-digestible food ingredients that are utilized by host microorganisms leading to a health benefit. Prebiotic effects include improving defense against pathogens, improving gut microbiota composition, immune modulation, mineral absorption, bowel function, metabolic effects and satiety. Since prebiotics are found in very low amounts in foods, scientists are trying to produce these ingredients on an industrial scale. In this review, the production of probiotics and prebiotics and their effects on intestinal and skin health have been studied.

Kaynakça

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Yıl 2021, Cilt: 16 Sayı: 64, 263 - 289, 28.11.2022

Öz

İnsan bağırsak mikrobiyotası sağlığın ayrılmaz bir parçasıdır ve çeşitli hastalıklarla ilişkilendirilmektedir. Sağlam bir bağırsak bariyeri korumak, doku hasarı, patojen enfeksiyonları ve hastalık gelişiminin önlenmesinde, ayrıca bağırsak sağlığı ve genel olarak sağlık durumunun iyileştirmesinde önemli bir rol oynamaktadır. Bağırsak bariyerin işlevinin bozulması durumunda, bakteriyel translokasyonu meydana gelebilmektedir. Probiyotikler, sağlığı geliştirmek için vücuda alınan canlı mikroorganizmalardır. Probiyotiklerin faydaları, onların bağırsak mikrobiyotası üzerindeki etkilerine dayanmaktadır. Bağırsak, karaciğer ve pankreas hastalıklarının tedavisinde, atopik dermatitinin (AD) iyileştirmesinde ve enfeksiyonların önlenmesinde probiyotiklerin kullanması hakkında çok sayıda çalışma yapılmıştır. Laktik asit ve bifidobakteri gibi probiyotikler, gıda endüstrisinde yaygın olarak üretilmekte ve bu maddelere yönelik müşteri talebi sürekli artmaktadır. Prebiyotikler, konakçı mikroorganizmalar tarafından kullanılan ve sağlık açısından fayda sağlayan sindirilemeyen gıda bileşenleridir. Prebiyotik etkileri arasında, patojenlere karşı savunmasının ve bağırsak mikrobiyota bileşiminin iyileştirilmesi, bağışıklık modülasyonu, mineral emilimi ve bağırsak işlevinin geliştirilmesi, metabolik etkiler ve tokluk bulunmaktadır. Prebiyotikler gıdalarda çok düşük miktarlarda bulundukları için bilim adamları bu bileşenleri sanayi ölçekte üretmeye çalışıyorlardır. Bu derlemede probiyotikler ve prebiyotiklerin üretimi ve bağırsak ve cilt sağlığı üzerindeki etkisi incelenmiştir.

Kaynakça

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  • Weston, S., Halbert, A., Richmond, P., & Prescott, S. L. (2005). Effects of probiotics on atopic dermatitis: a randomised controlled trial. Archives of Disease in Childhood, 90(9), 892–897.
  • Yin, J., Li, G., Ren, X., & Herrler, G. (2007). Select what you need: a comparative evaluation of the advantages and limitations of frequently used expression systems for foreign genes. Journal of Biotechnology, 127(3), 335–347.
  • Yoon, S.-H., Mukerjea, R., & Robyt, J. F. (2003). Specificity of yeast (Saccharomyces cerevisiae) in removing carbohydrates by fermentation. Carbohydrate Research, 338(10), 1127–1132.
  • Yun, J. W. (1996). Fructooligosaccharides—occurrence, preparation, and application. Enzyme and Microbial Technology, 19(2), 107–117.
  • Yun, J. W., Lee, M. G., & Song, S. K. (1994). Batch production of high-content fructo-oligosaccharides from sucrose by the mixed-enzyme system of β-fructofuranosidase and glucose oxidase. Journal of Fermentation and Bioengineering, 77(2), 159–163.
Toplam 110 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Makaleler
Yazarlar

Faruk Galyon 0000-0002-1304-4657

Candan Varlık 0000-0002-6199-1974

Yayımlanma Tarihi 28 Kasım 2022
Gönderilme Tarihi 18 Ocak 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 16 Sayı: 64

Kaynak Göster

APA Galyon, F., & Varlık, C. (2022). Probiyotikler, Prebiyotikler ve bunların bağırsak ve cilt sağlığı üzerinde etkileri. Anadolu Bil Meslek Yüksekokulu Dergisi, 16(64), 263-289.


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