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THE ANALYTICAL INSRUMENTATION METHODS NEEDED FOR MODERN FORENSIC TOXICOLOGY LABORATORY

Year 2017, Volume: Volume 2 Issue: İssue 1 (1) - 2.İnternational Congress Of Forensic Toxicology, 112 - 112, 16.02.2017

Abstract

The use of
advanced analytical techniques for a modern forensic toxicology laboratory is
indispensable. The current presentation aims to present the methodological
theory and current technology for the determination of chemicals in biological
tissues, fluids and environment. The goal of analytical measurements is to
attain coherent, confidential, sensitive and right data. For achieving this
goal, method is required to be validated. This procedure should be done
separately for each matrix and laboratory. The most modern instrumentations
used in forensic toxicology laboratory are Gas Chromatograph–Quadrupole Mass
Spectrometer (GC–QMS), GC–Ion Trap MS (GC–ITMS and GC–MS/MS, Liquid
Chromatograph–Mass Spectrometers (LC–ITMS and LC–MS–MS), Magnetic Sector MS and
GC–Combustion Isotope MS, Time-of-Flight Mass Spectrometers (TOF-MS), Fourier
Transform Ion Cyclotron Resonance Mass Spectrometers (FTMS) and Orbitrap™,
Cyclic Voltammetry and Pulsed Electrochemical Detectors (PED) and Capillary
Electrophoresis. The QMS, ITMS, and LC–MS allow identifying and quantifying a
number of toxicants such as small molecular weight chemicals and steroids in
environment and biological tissues. Innovations like lower column diameter
size, high ignition rate furnaces, high compression carrying gas control and
choice of more effective capillary columns have diminished the time needed for
determination. Facilitating of software design for LC–MS and LC–MS/MS allow
easier and faster analysis. Hybrid tools are important for the growing needs of
forensic laboratories in criminal investigations. FTMS have disadvantages such
as expensive and need of ultra-low vacuum. However, Orbitrap is a new
technology, and can be use instead of FTMS.

References

  • Ayhan FILAZI, Begum YURDAKOK-DIKMEN
  • Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Ankara University, Turkey
Year 2017, Volume: Volume 2 Issue: İssue 1 (1) - 2.İnternational Congress Of Forensic Toxicology, 112 - 112, 16.02.2017

Abstract

References

  • Ayhan FILAZI, Begum YURDAKOK-DIKMEN
  • Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Ankara University, Turkey
There are 2 citations in total.

Details

Journal Section Articles
Authors

Ayhan Fılazı

Begum Yurdakok-dıkmen This is me

Publication Date February 16, 2017
Published in Issue Year 2017 Volume: Volume 2 Issue: İssue 1 (1) - 2.İnternational Congress Of Forensic Toxicology

Cite

APA Fılazı, A., & Yurdakok-dıkmen, B. (2017). THE ANALYTICAL INSRUMENTATION METHODS NEEDED FOR MODERN FORENSIC TOXICOLOGY LABORATORY. The Turkish Journal Of Occupational / Environmental Medicine and Safety, Volume 2(İssue 1 (1), 112-112.
AMA Fılazı A, Yurdakok-dıkmen B. THE ANALYTICAL INSRUMENTATION METHODS NEEDED FOR MODERN FORENSIC TOXICOLOGY LABORATORY. turjoem. February 2017;Volume 2(İssue 1 (1):112-112.
Chicago Fılazı, Ayhan, and Begum Yurdakok-dıkmen. “THE ANALYTICAL INSRUMENTATION METHODS NEEDED FOR MODERN FORENSIC TOXICOLOGY LABORATORY”. The Turkish Journal Of Occupational / Environmental Medicine and Safety Volume 2, no. İssue 1 (1) (February 2017): 112-12.
EndNote Fılazı A, Yurdakok-dıkmen B (February 1, 2017) THE ANALYTICAL INSRUMENTATION METHODS NEEDED FOR MODERN FORENSIC TOXICOLOGY LABORATORY. The Turkish Journal Of Occupational / Environmental Medicine and Safety Volume 2 İssue 1 (1) 112–112.
IEEE A. Fılazı and B. Yurdakok-dıkmen, “THE ANALYTICAL INSRUMENTATION METHODS NEEDED FOR MODERN FORENSIC TOXICOLOGY LABORATORY”, turjoem, vol. Volume 2, no. İssue 1 (1), pp. 112–112, 2017.
ISNAD Fılazı, Ayhan - Yurdakok-dıkmen, Begum. “THE ANALYTICAL INSRUMENTATION METHODS NEEDED FOR MODERN FORENSIC TOXICOLOGY LABORATORY”. The Turkish Journal Of Occupational / Environmental Medicine and Safety VOLUME 2/İssue 1 (1) (February 2017), 112-112.
JAMA Fılazı A, Yurdakok-dıkmen B. THE ANALYTICAL INSRUMENTATION METHODS NEEDED FOR MODERN FORENSIC TOXICOLOGY LABORATORY. turjoem. 2017;Volume 2:112–112.
MLA Fılazı, Ayhan and Begum Yurdakok-dıkmen. “THE ANALYTICAL INSRUMENTATION METHODS NEEDED FOR MODERN FORENSIC TOXICOLOGY LABORATORY”. The Turkish Journal Of Occupational / Environmental Medicine and Safety, vol. Volume 2, no. İssue 1 (1), 2017, pp. 112-.
Vancouver Fılazı A, Yurdakok-dıkmen B. THE ANALYTICAL INSRUMENTATION METHODS NEEDED FOR MODERN FORENSIC TOXICOLOGY LABORATORY. turjoem. 2017;Volume 2(İssue 1 (1):112-.