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Ağız mukozasının sık görülen premalign lezyonları

Year 2018, Volume: 10 Issue: 2, 190 - 200, 01.06.2018

İnci Karaca Hümeyra Yazar

https://doi.org/10.21601/ortadogutipdergisi.340599

Abstract

Dünya
Sağlık Örgütü (DSÖ), prekanserleri; prekanseröz (premalign) lezyonlar ve
prekanseröz (premalign) durumlar olarak sınıflandırmıştır. Premalign lezyonlar; görünüşte
benzer özellikteki dokuya göre kanserin oluşma olasılığı daha yüksek olan,
morfolojik olarak değiştirilmiş bir doku" olarak tanımlanmaktadır.
Lökoplaki, eritroplaki, ters sigara ile ilişkili palatal lezyonlar ve aktinik
şelitis premalign lezyonlara örneklerdir. Premalign durumlara örnek olarak ise
oral submuköz  fibrozis, liken planus,
diskoit lupus eritematosus, sideropenik disfaji, epidermoliz bulloza ve
kseroderma pigmentosum verilebilir.



Bu
derlemede; en sık rastlanan premalign lezyonlardan olan lökoplaki ve
eritroplaki ile premalign durumlardan olan liken planus hakkında bilgi verilmesi
amaçlanmıştır.



Keywords

premalign eritroplaki lökoplaki liken planus

References

  • Axell T, Holmstrup P, Kramer IRH, et al. International seminar on oral leukoplakia and associated lesions related to tobacco habits. Community Dent Oral Epidemiol 1984;12(3):145-154.
  • Vigneswaran N, El-Naggar AK. Early detection and diagnosis of oral premalignant squamous mucosal lesions. Biomedical Optics in Otorhinolaryngology 2016; 601-17.
  • Gendelman, H, Actis AB, Ouri HO. Neodymium-YAG and CO2 lasers in treatment of pre-cancerous lesions of the oral cavity. Acta Stomatol Belg 1993; 90(2):95-101.
  • Lestón JS, Dios PD. Diagnostic clinical aids in oral cancer. Oral Oncol 2010;46(6):418-22.
  • Karabulut A, Reibel J, Therkildsen MH, et al. Observer variability in the histologic assessment of oral premalignant lesions. J Oral Pathol Med 1995; 24(5): 198-200.
  • Pindborg JJ, Reibel J, Holmstrup P. Subjectivity in evaluating oral epithelial dysplasia, carcinoma in situ and initial carcinoma. J Oral Pathol Med 1985; 14(9): 698-708.
  • Vedtofte P, Holmstrup P, Hjørting-Hansen E, et al. Surgical treatment of premalignant lesions of the oral mucosa. Int J Oral Maxillofac Surg 1987;16(6): 656-664.
  • Frame JW, Gupta AD, Dalton GA, et al. Use of the carbon dioxide laser in the management of premalignant lesions of the oral mucosa. The Journal of Laryngology & Otology 1984; 98(12): 1251-1260.
  • The Oral Cancer Foundation. Available from: http://oralcancerfoundation.org/cdc/histopathology-biology-markers/ 2017.
  • Shafer WG, Hine K, Levy BM. A Textbook of oral pathology. 4th ed. WB Saunders Company, Philedelphia;1983.
  • Wood NK, Goaz PW. Differential diagnosis of oral lesions. Mosby Elsevier Health Science; 1985.
  • Günhan Ö. Oral ve Maksillofasiyal Patoloji.1.baskı. Qintessence Publishing, Ankara; 2015;190-200
  • World Health Organization, International Agency for Research on Cancer, Oral Atlas. Available from: http://screening.iarc.fr/atlasoral_list.php?cat=B&lang=1 IARC 2017.
  • Holmstrup P, Thorn JJ, Rindum J, et al. Malignant development of lichen planus‐affected oral mucosa. J Oral Pathol Med 1988; 17(5):219-225.
  • Lavelle CLB, Proctor DB. Clinical pathology of the oral mucosa. Medical Department Harper & Row, Publishers Hagerstown, Maryland, New York, San Francisco, London; 1978.
  • Warnakulasuriya S, Johnson N, Waal I. Nomenclature and classification of potentially malignant disorders of the oral mucosa. J Oral Pathol Med 2007; 36(10): 575-580.
  • More CB, Peter R, Shilu K, et al. Oral leukoplakia: An overview with evidence based management. International Journal of Oral and Maxillofacial Diseases 2016; 1(3):14-19.
  • Williams LJ. Oral cancer and precancer: Clinical features. Br Dent J 1990; 168: 13-17. Flynn MB, White M, Tabah RJ. Use of carbon dioxide laser for the treatment of premalignant lesions of the oral mucosa. J Surg Oncol 1988; 37(4):232-234.
  • Weidner N, Cote RJ, Suster S, et al. Modern surgical pathology. Elsevier Health Sciences. (2009). Van der Waal I. Leukoplakia. Orofacial Disorders: Springer; 2017; 3-13.
  • Chung CH, Yang YH, Wang TY, et al. Oral precancerous disorders associated with areca quid chewing, smoking, and alcohol drinking in southern Taiwan. J Oral Pathol Med 2005; 34(8): 460-466.
  • Van der Waal I. Diseases of the Oral Mucosa and Soft Tissues: General Aspects. Atlas of Oral Diseases: Springer; 2016. 7-66.
  • Abidullah M, Kiran G, Gaddikeri K, et al. Leuloplakia-Review of a potentially malignant disorder. Journal of clinical and diagnostic research: JCDR 2014;8(8):1-4.
  • Olinici D, Gheucă-Solovăstru L, Țăranu T, et al. Corelations between the clinical and morfological aspects and the molecular markers in the malignant transformation of the oral leukoplakias. Romanian Journal of Oral Rehabilitation 2016;8(2): 80-86
  • Luo CW, Roan CH, Liu CJ. Human papillomaviruses in oral squamous cell carcinoma and pre-cancerous lesions detected by PCR-based gene-chip array. Int J Oral Maxillofac Surg 2007; 36(2):153-158.
  • Bhargava A, Shakeel M, Srivastava A, et al. Role of human papilloma virus in oral leukoplakia. Indian J Cancer 2016;53(1):206-9
  • Regezi JA, Sciubba JJ, Jordan RC. Oral Pathology. Clinical Pathologic Correlations. Journal der Deutschen Dermatologischen Gesellschaft 2008;6(7):607. Shah N, Ray JG, Kundu S, et al. Surgical management of chronic hyperplastic candidiasis refractory to systemic antifungal treatment. Journal of Laboratory Physicians 2017;9(2):136-9
  • Mogedas-Vegara A, Hueto-Madrid J-A, Chimenos-Küstner E, et al. Oral leukoplakia treatment with the carbon dioxide laser: A systematic review of the literature. J Craniomaxillofac Surg 2016;44(4):331-6.
  • McCullough M, Prasad G, Farah C. Oral mucosal malignancy and potentially malignant lesions: an update on the epidemiology, risk factors, diagnosis and management. Aust Dent J 2010;55(s1):61-5.
  • Patait M, Nikate U, Saraf K, et al. Oral erythroplakia–A case report. International Journal of Applied Dental Sciences 2016; 2(4): 79-82.
  • Reichart PA, Philipsen HP. Oral erythroplakia—a review. Oral Oncol 2005;41(6):551-61.
  • Katz RW, Brahim JS, Travis WD. Oral squamous cell carcinoma arising in a patient with long-standing lichen planus: a case report. Oral Surg Oral Med Oral Pathol 1990; 70(3): 282-285.
  • Lacy MF, Reade PC, Hay KD. Lichen planus: a theory of pathogenesis. Oral Surg Oral Med Oral Pathol 1983; 56(5): 521-526.
  • Silverman SM, Gorsky M, Lozada-Nur F. A prospective follow-up study of 570 patients with oral lichen planus: persistence, remission, and malignant association. Oral Surg Oral Med Oral Pathol 1985; 60(1): 30-34.
  • Murti PR, Daftary DK, Bhonsle RB, et al. Malignant potential of oral lichen planus: Observations in 722 patients from India. J Oral Pathol Med 1986; 15(2): 71-77.
  • Silverman S, Gorsky M, Lozada-Nur F, et al. Prospective study of findings and management in 214 patients with oral lichen planus. Oral Surg Oral Med Oral Pathol 1991; 72(6): 665-670.
  • Scully C, Carrozzo M. Oral mucosal disease: Lichen planus. Br J Oral Maxillofac Surg 2008; 46(1): 15-21.
  • Lodi G, Scully C, Carrozzo M, et al. Current controversies in oral lichen planus: Report of an international consensus meeting. Part 2. Clinical management and malignant transformation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005; 100(2): 164-178.
  • Ingafou M, Leao JC, Porter SR, et al. Oral lichen planus: A retrospective study of 690 British patients. Oral Diseases 2006; 12(5): 463-468.
  • Aghahosseini F, Arbabi‐Kalati F, Fashtami LA, et al. Methylene blue‐mediated photodynamic therapy: A possible alternative treatment for oral lichen planus. Lasers Surg Med 2006; 38(1): 33-38.

Common premalignant lesions of the oral mucosa

Year 2018, Volume: 10 Issue: 2, 190 - 200, 01.06.2018

İnci Karaca Hümeyra Yazar

https://doi.org/10.21601/ortadogutipdergisi.340599

Abstract

The
World Health Organization (WHO) has accepted the classification of precancers
into precancerous (premalign) lesions and precancerous (premalign) conditions.
There is general agreement that a premalign lesion is defined as “a
morphologically altered tissue in which cancer is more likely to occur than its
apparently normal counterpart. Examples for premalign lesions are leukoplakia, erythroplakia, palatal lesions associated with reverse smoking and actinic cheiloses. Examples for premalign conditions include oral submucous fibrosis, lichen planus, discoid lupus erythematosus, sideropenic dysphagia, epidermolysis bullosa and xeroderma pigmentosa.

In
this rewiev, we aimed to give information about leukoplakia and erythroplakia
which are the most common premalign lesions and lichen planus that is one of
the premalign conditions.





 

Keywords

premalign erythroplakia leukoplakia lichen planus

References

  • Axell T, Holmstrup P, Kramer IRH, et al. International seminar on oral leukoplakia and associated lesions related to tobacco habits. Community Dent Oral Epidemiol 1984;12(3):145-154.
  • Vigneswaran N, El-Naggar AK. Early detection and diagnosis of oral premalignant squamous mucosal lesions. Biomedical Optics in Otorhinolaryngology 2016; 601-17.
  • Gendelman, H, Actis AB, Ouri HO. Neodymium-YAG and CO2 lasers in treatment of pre-cancerous lesions of the oral cavity. Acta Stomatol Belg 1993; 90(2):95-101.
  • Lestón JS, Dios PD. Diagnostic clinical aids in oral cancer. Oral Oncol 2010;46(6):418-22.
  • Karabulut A, Reibel J, Therkildsen MH, et al. Observer variability in the histologic assessment of oral premalignant lesions. J Oral Pathol Med 1995; 24(5): 198-200.
  • Pindborg JJ, Reibel J, Holmstrup P. Subjectivity in evaluating oral epithelial dysplasia, carcinoma in situ and initial carcinoma. J Oral Pathol Med 1985; 14(9): 698-708.
  • Vedtofte P, Holmstrup P, Hjørting-Hansen E, et al. Surgical treatment of premalignant lesions of the oral mucosa. Int J Oral Maxillofac Surg 1987;16(6): 656-664.
  • Frame JW, Gupta AD, Dalton GA, et al. Use of the carbon dioxide laser in the management of premalignant lesions of the oral mucosa. The Journal of Laryngology & Otology 1984; 98(12): 1251-1260.
  • The Oral Cancer Foundation. Available from: http://oralcancerfoundation.org/cdc/histopathology-biology-markers/ 2017.
  • Shafer WG, Hine K, Levy BM. A Textbook of oral pathology. 4th ed. WB Saunders Company, Philedelphia;1983.
  • Wood NK, Goaz PW. Differential diagnosis of oral lesions. Mosby Elsevier Health Science; 1985.
  • Günhan Ö. Oral ve Maksillofasiyal Patoloji.1.baskı. Qintessence Publishing, Ankara; 2015;190-200
  • World Health Organization, International Agency for Research on Cancer, Oral Atlas. Available from: http://screening.iarc.fr/atlasoral_list.php?cat=B&lang=1 IARC 2017.
  • Holmstrup P, Thorn JJ, Rindum J, et al. Malignant development of lichen planus‐affected oral mucosa. J Oral Pathol Med 1988; 17(5):219-225.
  • Lavelle CLB, Proctor DB. Clinical pathology of the oral mucosa. Medical Department Harper & Row, Publishers Hagerstown, Maryland, New York, San Francisco, London; 1978.
  • Warnakulasuriya S, Johnson N, Waal I. Nomenclature and classification of potentially malignant disorders of the oral mucosa. J Oral Pathol Med 2007; 36(10): 575-580.
  • More CB, Peter R, Shilu K, et al. Oral leukoplakia: An overview with evidence based management. International Journal of Oral and Maxillofacial Diseases 2016; 1(3):14-19.
  • Williams LJ. Oral cancer and precancer: Clinical features. Br Dent J 1990; 168: 13-17. Flynn MB, White M, Tabah RJ. Use of carbon dioxide laser for the treatment of premalignant lesions of the oral mucosa. J Surg Oncol 1988; 37(4):232-234.
  • Weidner N, Cote RJ, Suster S, et al. Modern surgical pathology. Elsevier Health Sciences. (2009). Van der Waal I. Leukoplakia. Orofacial Disorders: Springer; 2017; 3-13.
  • Chung CH, Yang YH, Wang TY, et al. Oral precancerous disorders associated with areca quid chewing, smoking, and alcohol drinking in southern Taiwan. J Oral Pathol Med 2005; 34(8): 460-466.
  • Van der Waal I. Diseases of the Oral Mucosa and Soft Tissues: General Aspects. Atlas of Oral Diseases: Springer; 2016. 7-66.
  • Abidullah M, Kiran G, Gaddikeri K, et al. Leuloplakia-Review of a potentially malignant disorder. Journal of clinical and diagnostic research: JCDR 2014;8(8):1-4.
  • Olinici D, Gheucă-Solovăstru L, Țăranu T, et al. Corelations between the clinical and morfological aspects and the molecular markers in the malignant transformation of the oral leukoplakias. Romanian Journal of Oral Rehabilitation 2016;8(2): 80-86
  • Luo CW, Roan CH, Liu CJ. Human papillomaviruses in oral squamous cell carcinoma and pre-cancerous lesions detected by PCR-based gene-chip array. Int J Oral Maxillofac Surg 2007; 36(2):153-158.
  • Bhargava A, Shakeel M, Srivastava A, et al. Role of human papilloma virus in oral leukoplakia. Indian J Cancer 2016;53(1):206-9
  • Regezi JA, Sciubba JJ, Jordan RC. Oral Pathology. Clinical Pathologic Correlations. Journal der Deutschen Dermatologischen Gesellschaft 2008;6(7):607. Shah N, Ray JG, Kundu S, et al. Surgical management of chronic hyperplastic candidiasis refractory to systemic antifungal treatment. Journal of Laboratory Physicians 2017;9(2):136-9
  • Mogedas-Vegara A, Hueto-Madrid J-A, Chimenos-Küstner E, et al. Oral leukoplakia treatment with the carbon dioxide laser: A systematic review of the literature. J Craniomaxillofac Surg 2016;44(4):331-6.
  • McCullough M, Prasad G, Farah C. Oral mucosal malignancy and potentially malignant lesions: an update on the epidemiology, risk factors, diagnosis and management. Aust Dent J 2010;55(s1):61-5.
  • Patait M, Nikate U, Saraf K, et al. Oral erythroplakia–A case report. International Journal of Applied Dental Sciences 2016; 2(4): 79-82.
  • Reichart PA, Philipsen HP. Oral erythroplakia—a review. Oral Oncol 2005;41(6):551-61.
  • Katz RW, Brahim JS, Travis WD. Oral squamous cell carcinoma arising in a patient with long-standing lichen planus: a case report. Oral Surg Oral Med Oral Pathol 1990; 70(3): 282-285.
  • Lacy MF, Reade PC, Hay KD. Lichen planus: a theory of pathogenesis. Oral Surg Oral Med Oral Pathol 1983; 56(5): 521-526.
  • Silverman SM, Gorsky M, Lozada-Nur F. A prospective follow-up study of 570 patients with oral lichen planus: persistence, remission, and malignant association. Oral Surg Oral Med Oral Pathol 1985; 60(1): 30-34.
  • Murti PR, Daftary DK, Bhonsle RB, et al. Malignant potential of oral lichen planus: Observations in 722 patients from India. J Oral Pathol Med 1986; 15(2): 71-77.
  • Silverman S, Gorsky M, Lozada-Nur F, et al. Prospective study of findings and management in 214 patients with oral lichen planus. Oral Surg Oral Med Oral Pathol 1991; 72(6): 665-670.
  • Scully C, Carrozzo M. Oral mucosal disease: Lichen planus. Br J Oral Maxillofac Surg 2008; 46(1): 15-21.
  • Lodi G, Scully C, Carrozzo M, et al. Current controversies in oral lichen planus: Report of an international consensus meeting. Part 2. Clinical management and malignant transformation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005; 100(2): 164-178.
  • Ingafou M, Leao JC, Porter SR, et al. Oral lichen planus: A retrospective study of 690 British patients. Oral Diseases 2006; 12(5): 463-468.
  • Aghahosseini F, Arbabi‐Kalati F, Fashtami LA, et al. Methylene blue‐mediated photodynamic therapy: A possible alternative treatment for oral lichen planus. Lasers Surg Med 2006; 38(1): 33-38.
There are 39 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Review
Authors

İnci Karaca

Hümeyra Yazar

Publication Date June 1, 2018
Published in Issue Year 2018 Volume: 10 Issue: 2

Cite

Vancouver Karaca İ, Yazar H. Ağız mukozasının sık görülen premalign lezyonları. omj. 2018;10(2):190-20.

e-ISSN: 2548-0251

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