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Bir inekte Ovine Herpesvirüs-2’nin neden olduğu Sığır Gangrenli Nezlesi olgusu

Year 2020, Volume: 31 Issue: 1, 82 - 86, 07.06.2020
https://doi.org/10.35864/evmd.715431

Abstract

Sığır gangrenli nezlesi (SGN) (malign kataral ateş), evcil sığır ve yabani geviş getirenlerin önemli viral bir hastalığıdır. Sunulan olguda, 4 yaşlı Holştayn ırkı bir inekte Ovine Herpesvirüs-2’nin (OvHV-2) neden olduğu SGN enfeksiyonu patolojik ve PCR bulgularıyla birlikte tanımlanmıştır. Mikroskopik incelemede, tüm doku ve organlarda fibrinoid nekrotik vaskülitis, beynin damar duvarlarında yangısal değişiklikler (pons, serebrum ve meninksler), oral mukozada ülseratif değişiklikler, böbreğin korteksinde glomerüllerin çevresinde interstisyumda hafif yangısal hücre infiltrasyonları ve kalpteki kas demetleri arasında yaygın ödem görüldü. OvHV-2 nükleik asitlerinin varlığını belirlemek amacıyla PCR yöntemi uygulandı ve 386 bp ürünü, OvHV-2'nin Pol gen bölgesini kopyalayan primer sekansları ile elde edildi. Bu bulgular ile sunulan olguda koyunla ilişkili SGN tanısı doğrulandı.

References

  • Baxter SI, Pow I, Bridgen A, Reid HW. (1993). PCR detection of the sheep-associated agent of malignant catarrhal fever. Arch Virol. 132, 145–159.
  • Bedelian C, Nkedianye D, Herrero M. (2007). Maasai perception of the impact and incidence of malignant catarrhal fever (MCF) in southern Kenya. Prev Vet Med. 78, 296–316.
  • Boye M, Kamstrup S, Dalsgaard K. (1991). Specific sequence amplification of bovine virus diarrhea virus (BVDV) and hog cholera virus and sequencing of BVDV nucleic acid. Vet Microbiol. 29, 1–13.
  • Crawford TB, Li H, Rosenburg SR, Norhausen RW, Garner MM. (2002). Mural folliculitis and alopecia caused by infection with goat-associated malignant catarrhal fever virus in two Sika deer. J Am Vet Med Assoc. 221, 843–847.
  • Dabak M, Bulut H. (2003). Outbreak of malignant catarrhal fever in cattle in Turkey. Vet Rec. 152, 240–241.
  • Davison AJ, Eberle R, Ehlers B, Hayward GS, Mc Geoch DJ, Minson AC, Pellett PE, Roizman B, Studdert MJ, Thiry E. (2009). The order Herpesvirales. Arch Virol. 154, 171-177.
  • Esteves PA, Dellagostin O, Pinto LS, Silva AD, Spilki FR, Ciacci-Zanella JR, Hubner SO, Puentes R, Maisonnave J, Franco AC, Rijsewijk FAM, Batista HBCR, TTeixeria TF, Dezen D, Oliveira AP, David C, Arns CW, Roeh PM. (2008). Phylogenetic comparison of the carboxy-terminal region of glycoprotein C (gC) of bovine herpesviruses (BoHV)1.1, 1.2 and 5 from South America (SA). Virus Res. 131, 16-22.
  • Flach EJ, Reid H, Pow I, Klemt A. (2002). Gamma herpesvirus carrier status of captive artiodactyls. Res Vet Sci. 73, 93–99.
  • Kırbaş A, Oruç E, Özkanlar Y, Sözdutmaz İ, Aktaş MS, Sağlam YS. (2013). Sheep-Associated Malignant Catarrhal Fever: First report in a Calf in Northeastern Turkey. Israel J Vet Med. 68 (3): 195-200.
  • Li H, O’Toole D, Kim O, Oaks JL, Crawford TB. (2005). Malignant catarrhal fever-like disease in sheep after intranasal inoculation with ovine herpesvirus-2. J Vet Diagn Invest. 17, 171–175.
  • Russell GC, Stewart JP, Haig DM. (2009). Malignant catarrhal fever: A review.Vet J. 179, 324-335.
  • Traul DL, Elias S, Taus NS, Herrmann LM, Oaks JL, Li H. (2005). A real-time PCR assay for measuring alcelaphine herpesvirus-1 DNA. J Virol Methods. 129, 186–190.
  • Yıldırım Y, Dağalp SB, Yılmaz V, Majarashin ARF. (2012). Molecular characterisation of ovine herpesvirus type 2 (OvHV-2) in Turkey. Acta Vet Hung. 60 (4): 521–527.

Malignant Catarrhal Fever caused by Ovine Herpesvirus-2 in a cow

Year 2020, Volume: 31 Issue: 1, 82 - 86, 07.06.2020
https://doi.org/10.35864/evmd.715431

Abstract

Malignant catarrhal fever (MCF) has been defined as a viral disease of domestic cattle and wild ruminants. We report a case of MCF caused by ovine herpesvirus-2 (OvHV-2) in a 4-year-old female Holstein cow. Microscopic examination showed that fibrinoid necrotic vasculitis in all tissues and organs; inflammatory changes in the vessel walls of the brain (pons, cerebrum and meninges); ulcerative changes in the oral mucosa; mild inflammatory cell infiltrations around the glomeruli and interstitium in the cortex of the kidney; widespread edema between the muscle bundles in the heart. PCR was performed to determine the presence of ovine herpesvirus-2 nucleic acids and 386 bp product was obtained by primer sequences that replicated the Pol gene region of OvHV-2. This PCR finding confirmed our diagnosis as sheep-associated MCF (SA-MCF).

References

  • Baxter SI, Pow I, Bridgen A, Reid HW. (1993). PCR detection of the sheep-associated agent of malignant catarrhal fever. Arch Virol. 132, 145–159.
  • Bedelian C, Nkedianye D, Herrero M. (2007). Maasai perception of the impact and incidence of malignant catarrhal fever (MCF) in southern Kenya. Prev Vet Med. 78, 296–316.
  • Boye M, Kamstrup S, Dalsgaard K. (1991). Specific sequence amplification of bovine virus diarrhea virus (BVDV) and hog cholera virus and sequencing of BVDV nucleic acid. Vet Microbiol. 29, 1–13.
  • Crawford TB, Li H, Rosenburg SR, Norhausen RW, Garner MM. (2002). Mural folliculitis and alopecia caused by infection with goat-associated malignant catarrhal fever virus in two Sika deer. J Am Vet Med Assoc. 221, 843–847.
  • Dabak M, Bulut H. (2003). Outbreak of malignant catarrhal fever in cattle in Turkey. Vet Rec. 152, 240–241.
  • Davison AJ, Eberle R, Ehlers B, Hayward GS, Mc Geoch DJ, Minson AC, Pellett PE, Roizman B, Studdert MJ, Thiry E. (2009). The order Herpesvirales. Arch Virol. 154, 171-177.
  • Esteves PA, Dellagostin O, Pinto LS, Silva AD, Spilki FR, Ciacci-Zanella JR, Hubner SO, Puentes R, Maisonnave J, Franco AC, Rijsewijk FAM, Batista HBCR, TTeixeria TF, Dezen D, Oliveira AP, David C, Arns CW, Roeh PM. (2008). Phylogenetic comparison of the carboxy-terminal region of glycoprotein C (gC) of bovine herpesviruses (BoHV)1.1, 1.2 and 5 from South America (SA). Virus Res. 131, 16-22.
  • Flach EJ, Reid H, Pow I, Klemt A. (2002). Gamma herpesvirus carrier status of captive artiodactyls. Res Vet Sci. 73, 93–99.
  • Kırbaş A, Oruç E, Özkanlar Y, Sözdutmaz İ, Aktaş MS, Sağlam YS. (2013). Sheep-Associated Malignant Catarrhal Fever: First report in a Calf in Northeastern Turkey. Israel J Vet Med. 68 (3): 195-200.
  • Li H, O’Toole D, Kim O, Oaks JL, Crawford TB. (2005). Malignant catarrhal fever-like disease in sheep after intranasal inoculation with ovine herpesvirus-2. J Vet Diagn Invest. 17, 171–175.
  • Russell GC, Stewart JP, Haig DM. (2009). Malignant catarrhal fever: A review.Vet J. 179, 324-335.
  • Traul DL, Elias S, Taus NS, Herrmann LM, Oaks JL, Li H. (2005). A real-time PCR assay for measuring alcelaphine herpesvirus-1 DNA. J Virol Methods. 129, 186–190.
  • Yıldırım Y, Dağalp SB, Yılmaz V, Majarashin ARF. (2012). Molecular characterisation of ovine herpesvirus type 2 (OvHV-2) in Turkey. Acta Vet Hung. 60 (4): 521–527.
There are 13 citations in total.

Details

Primary Language English
Subjects Veterinary Sciences
Journal Section Case Reports
Authors

Hamdi Avcı

Emrah İpek

Ali Rıza Babaoğlu

Erkmen Ekipmen

Ahmet Aydoğan

Publication Date June 7, 2020
Submission Date April 6, 2020
Published in Issue Year 2020 Volume: 31 Issue: 1

Cite

APA Avcı, H., İpek, E., Babaoğlu, A. R., Ekipmen, E., et al. (2020). Malignant Catarrhal Fever caused by Ovine Herpesvirus-2 in a cow. Etlik Veteriner Mikrobiyoloji Dergisi, 31(1), 82-86. https://doi.org/10.35864/evmd.715431

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