Review
Year 2017,
Volume: 14 Issue: 3, 209 - 218, 15.12.2017
Abstract
Bu derlemede balıkların önemli RNA viruslarına karşı geliştirilen revers genetik sistemler anlatılmıştır. Balık çift-liklerinde ekonomik kayıplara neden olan hastalıkların çoğu viral etkenlerden kaynaklanmaktadır. Bakteriyel, paraziter ve fungal balık hastalıkları çeşitli kemoterapötikler ile tedavi edilmesine karşın, viral hastalıkların tedavisi yapılamamak-tadır. Teknolojideki gelişmeler ve moleküler çalışmalar viral genoma müdahaleyi mümkün kılmıştır. Viral RNA geno-mundan canlı virus elde edilmesi “revers genetik” olarak isimlendirilmektedir. Revers genetik yöntemlerle viral RNA genomuna müdahale edilmesi, araştırmacılara birçok faydalar sağlamıştır. Revers genetik sistemler infeksiyöz salmon anemi virus (ISA), salmonid alfavirus (SAV), infeksiyöz hematopoetik nekrozis virus (IHNV), viral hemorajik septisemi virus (VHSV), infeksiyöz pankreatik nekrozis virus (IPNV) ve strip cek nervöz nekrozis virus (SJNNV) gibi balık RNA virusları için oluşturulmuştur. Revers genetik sistemlerin keşfi balıklarda patojen RNA virusları için büyük bir buluş ve saha araştırmaları için önemli bir araç olmuştur. Gelecek yıllarda revers genetik konusundaki çalışmaların artacağı ve bilim dünyası için ilgi odağı olacağı tahmin edilmektedir
Keywords
References
- 1. Albayrak H, Özan E. Gökkuşağı alabalıkla-rında (Oncorhynchus mykiss Walbaum, 1792) infeksiyöz pankreatik nekrozis ve in-feksiyöz hematopoietik nekrozis virus enfek-siyonlarının varlığının araştırılması. Ankara Üniv Vet Fak Derg 2010; 57(2): 125-9. 2. Ammayappan A, Lapatra ES, Vakharia NV. A vaccinia-virus-free reverse genetics sys-tem for infectious hematopoietic necrosis virus. J Virol Methods 2010; 167(2): 132-9. 3. Ammayappan A, Kurath G, Thompson MT, Vakharia NV. A Reverse genetics system for the Great Lakes strain of viral hemorrhagic septicemia virus: The NV gene is required for pathogenicity. Mar Biotechnol 2011; 13(4): 672-83. 4. Arda M. Temel Mikrobiyoloji. Birinci Baskı. Ankara: Medisan Yayınevi, 1997; p. 422-30. 5. Biacchesi S. The reverse genetics applied to fish RNA viruses. Vet Res 2011; 42 (12): 1-14. 6. Bremont M. ed. The World of Rhabdoviru-ses. First Edition. Berlin: Springer-Verlag, 2005; p. 119-41. 7. Bukreyev A, Skiadopoulos MH, Murphy BR, Collins PL. Nonsegmented negative-strand viruses as vaccine vectors. J Virol 2006; 80(21): 10293-306. 8. Dadar M, Peygham R, Rajabi-Memari H, Shapouri ASMR, Hasanzadeh R, Goudarzi LM, Vakharia NV. Infectious pancreatic nec-rosis virus (IPNV) based on deduced amina acid sequences of genom segment A and B cDNA. Iran J Fish Sci 2014; 13(3): 560-75. 9. Dadar M, Memari RH, Vakharia NV, Peygham R, Shapouri ASMR, Mohamma-dian T, Hasanzadeh R, Ghasemi M. Protec-tive and immunogenic effects of Escherichia coli-expressed infectious pancreatic necro-sis virus (IPNV) VP2-VP3 fusion protein in rainbow trout. Fish Shellfish Immun 2015; 47(1): 390-6. 10. Einer-Jensen K, Harmache A, Biacchesi S, Bremont M, Stegmann A, Lorenzen L. High virulence differences among phylogeneti-cally distinct isolates of the fish rhabdovirus viral hemorrhagic septicaemia virus are not explained by variability of the surface gly-coprotein G or the nonvirion protein Nv. J Gen Virol 2014; 95(Pt2): 307-16. 11. Finke S, Conzelmann KK. eds. The World of Rhabdoviruses. First Edition. Berlin: Sprin-ger-Verlag, 2005; p. 165-200. 12. Garcia-Rosado E, Markussen T, Kileng O, Baekkevold ES, Robertsen B, Mjaaland S, Rimstad E. Molecular and functional charac-terization of two infectious salmon anaemia virus (ISAV) proteins with type I interferon antagonizing activity. Virus Res 2008; 133(2): 228-38. 13. Heidari Z, Tinsley J, Bickerdike R, McLough-lin FM, Zou J, Martin MAS. Antiviral and me-tabolic gene expression responses to viral infection in Atlantic salmon (Salmo salar). Fish Shellfish Immun 2015; 42(2): 297-305. 14. Heppell J, Davis HL. Application of DNA vaccine technology to aquaculture. Adv Drug Deliv Rev 2000; 43(1): 29-43. 15. Iwamoto T, Mise K, Mori K, Arimoto M, Na-kai T, Okuno T. Establishment of an infecti-ous RNA transcription system for striped jack nervous necrosis virus, the type spe-cies of the betanodaviruses. J Gen Virol 2001; 82(11): 2653-62. 16. Jia P, Zheng CX, Shi JX, Kan FS, Wang JJ, He QJ, Zheng W, Yu L, Lan SW, Hua YQ, Liu H, Jin YN. Determination of the complete genome sequence of infectious hematopoie-tic necrosis virus (IHNV) Ch20101008 and viral molecular evolution in China. Infect Genet Evol 2014; 27(1): 418-31. 17. Julin K, Mennen S, Sommer AI. Study of virulence in field isolates of infectious panc-reatic necrosis virus obtained from the nort-hern part of Norway. J Fish Dis 2013; 36(2): 89-102. 18. Karlsen M, Andersen L, Blindheim HS, Rimstad E, Nylund A. A naturally occurring substitution in the E2 protein of salmonid alphavirus subtype 3 changes viral fitness. Virus Res 2015; 196(1): 79-86. 19. Kima HS, Yusuff S, Vakharia NV, Evensen O. Interchange of L polymerase protein between two strains of viral hemorrhagic septicemia virus (VHSV) genotype IV alters temperature sensitivities in vitro. Virus Res 2015; 195(1): 203-06. 20. Lauksund S, Greiner-Tollersrud L, Chang JC, Robertsen B. Infectious pancreatic nec-rosis virus proteins VP2, VP3, VP4 and VP5 antagonize IFNa1 promoter activation while VP1 induces IFNa1. Virus Res 2015; 196(1): 113-21. 21. Moriette C, Leberre M, Lamoureux A, Lai TL, Bremont M. Recovery of a recombinant salmonid alphavirus fully attenuated and protective for rainbow trout. J Virol 2006; 80(8):4088-98. 22. Munang’andu MH, Fredriksen NB, Mutoloki S, Brudeseth B, Kuo YT, Marjara SI, Dalmo AR, Evensena O. Comparison of vaccine efficacy for different antigen delivery sys-tems for infectious pancreatic necrosis virus vaccines in Atlantic salmon (Salmo salar L.) in a cohabitation challenge model. Vaccine 2012; 30(27): 4007-16. 23. Nishizawa T, Kinoshita S, Yoshimizu M. An approach for genogrouping of Japanese isolates of aquabirnaviruses in a new ge-nogroup, VII, based on the VP2/NS junction region. J Gen Virol 2005; 86(Pt7): 1973-78. 24. World Organisation for Animal Health (OİE). May 2013. Viral encephalopathy and retino-pathy. Manual of diagnostic tests for aquatic animals. Chapter 2.3.11.Erişim tarihi: 17.12. 2015. http://www.aait.org.cn/web/images/upload/2013/03/24/201303241612484062. pdf 25. Plant PK, Lapatra ES. Advances in fish vac-cine delivery. Dev Comp Immunol 2011; 35(12): 1256-62. 26. Rimstad E, Mjaaland S. Infectious salmon anaemia virus. APMIS 2002; 110(4): 273-82. 27. Santi N, Song H, Vakharia NV, Evensen O. Infectious pancreatic necrosis virus VP5 is dispensable for virulence and persistence. J Virol 2005; 79(14): 9206-16. 28. Song H, Santi N, Evensen O, Vakharia NV. Molecular determinants of infectious pancre-atic necrosis virus virulence and cell culture adaptation. J Virol 2005; 79 (16):10289-99. 29. Yao K, Vakharia NV. Generation of infecti-ous pancreatic necrosis virus from cloned cDNA. J Virol 1998; 72(11); 8913-20. 30. Takizawa N, Adachi K, Kobayashi N. Estab-lishment of reverse genetics system of beta- nodavirus for the efficient recovery of infecti-ous particles. J Virol Methods 2008; 151(2): 271-6. 31. Tam TP, Hoat CP, Hoa HTB, Hien TTN. Evaluation of the pathogenicity and immun response of nervous necrosis virus isolated in Vietnam. J Agr Sci Tech 2014; 4(1): 315-22. 32. Thoulouze MI, Bouguyon E, Carpentier C, Bremont M. Essential role of the NV protein of novirhabdovirus for pathogenicity in rain-bow trout. J Virol 2004; 78(8): 4098-107. 33. Toro-Ascuy D, Tambley C, Beltran C, Mas-cayano C, Sandoval N, Olivares E, Medina AR, Spencer E, Martína SCM. Development of a reverse genetic system for infectious salmon anemia virus: rescue of recombinant fluorescent virus by using salmon internal transcribed spacer region 1 as a novel pro-moter. Appl Environ Microbiol 2015; 81(4): 1210-24.
Year 2017,
Volume: 14 Issue: 3, 209 - 218, 15.12.2017
Abstract
In this review, the reverse genetics assessment of major fish viruses has been evaluated. The majority of the diseases causing economic losses in fish farms have been viral agents. Bacterial, parasitic and fungal fish disea-ses can be treated via various chemotherapeutics but viral diseases cannot be treated via these. Technological deve-lopments and molecular studies allowed manipulation of the viral genome. The live viruses were recovered from RNA genome. This applications is named as reverse genetics. The ability to manipulate the viral RNA genome trough rever-se genetics methods provided many benefits for researchers. The reverse genetics systems for the several fish RNA viruses were constructed; Infectious salmon anaemia virus (ISA), salmonid alphavirus (SAV), infectious hematopoietic necrosis virus (IHNV), viral hemorrhagic septicemia virus (VHSV), infectious pancreatic necrosis virus (IPNV) and stri-ped jack nervous necrosis virusu (SJNNV). Discovery of the reverse genetics on the pathogen fish RNA viruses have been a breakthrough and an important tool for field researches. In the next years forth, the studies of reverse genetics will increase and it supposes focus of attraction by the world of science.
Keywords
References
- 1. Albayrak H, Özan E. Gökkuşağı alabalıkla-rında (Oncorhynchus mykiss Walbaum, 1792) infeksiyöz pankreatik nekrozis ve in-feksiyöz hematopoietik nekrozis virus enfek-siyonlarının varlığının araştırılması. Ankara Üniv Vet Fak Derg 2010; 57(2): 125-9. 2. Ammayappan A, Lapatra ES, Vakharia NV. A vaccinia-virus-free reverse genetics sys-tem for infectious hematopoietic necrosis virus. J Virol Methods 2010; 167(2): 132-9. 3. Ammayappan A, Kurath G, Thompson MT, Vakharia NV. A Reverse genetics system for the Great Lakes strain of viral hemorrhagic septicemia virus: The NV gene is required for pathogenicity. Mar Biotechnol 2011; 13(4): 672-83. 4. Arda M. Temel Mikrobiyoloji. Birinci Baskı. Ankara: Medisan Yayınevi, 1997; p. 422-30. 5. Biacchesi S. The reverse genetics applied to fish RNA viruses. Vet Res 2011; 42 (12): 1-14. 6. Bremont M. ed. The World of Rhabdoviru-ses. First Edition. Berlin: Springer-Verlag, 2005; p. 119-41. 7. Bukreyev A, Skiadopoulos MH, Murphy BR, Collins PL. Nonsegmented negative-strand viruses as vaccine vectors. J Virol 2006; 80(21): 10293-306. 8. Dadar M, Peygham R, Rajabi-Memari H, Shapouri ASMR, Hasanzadeh R, Goudarzi LM, Vakharia NV. Infectious pancreatic nec-rosis virus (IPNV) based on deduced amina acid sequences of genom segment A and B cDNA. Iran J Fish Sci 2014; 13(3): 560-75. 9. Dadar M, Memari RH, Vakharia NV, Peygham R, Shapouri ASMR, Mohamma-dian T, Hasanzadeh R, Ghasemi M. Protec-tive and immunogenic effects of Escherichia coli-expressed infectious pancreatic necro-sis virus (IPNV) VP2-VP3 fusion protein in rainbow trout. Fish Shellfish Immun 2015; 47(1): 390-6. 10. Einer-Jensen K, Harmache A, Biacchesi S, Bremont M, Stegmann A, Lorenzen L. High virulence differences among phylogeneti-cally distinct isolates of the fish rhabdovirus viral hemorrhagic septicaemia virus are not explained by variability of the surface gly-coprotein G or the nonvirion protein Nv. J Gen Virol 2014; 95(Pt2): 307-16. 11. Finke S, Conzelmann KK. eds. The World of Rhabdoviruses. First Edition. Berlin: Sprin-ger-Verlag, 2005; p. 165-200. 12. Garcia-Rosado E, Markussen T, Kileng O, Baekkevold ES, Robertsen B, Mjaaland S, Rimstad E. Molecular and functional charac-terization of two infectious salmon anaemia virus (ISAV) proteins with type I interferon antagonizing activity. Virus Res 2008; 133(2): 228-38. 13. Heidari Z, Tinsley J, Bickerdike R, McLough-lin FM, Zou J, Martin MAS. Antiviral and me-tabolic gene expression responses to viral infection in Atlantic salmon (Salmo salar). Fish Shellfish Immun 2015; 42(2): 297-305. 14. Heppell J, Davis HL. Application of DNA vaccine technology to aquaculture. Adv Drug Deliv Rev 2000; 43(1): 29-43. 15. Iwamoto T, Mise K, Mori K, Arimoto M, Na-kai T, Okuno T. Establishment of an infecti-ous RNA transcription system for striped jack nervous necrosis virus, the type spe-cies of the betanodaviruses. J Gen Virol 2001; 82(11): 2653-62. 16. Jia P, Zheng CX, Shi JX, Kan FS, Wang JJ, He QJ, Zheng W, Yu L, Lan SW, Hua YQ, Liu H, Jin YN. Determination of the complete genome sequence of infectious hematopoie-tic necrosis virus (IHNV) Ch20101008 and viral molecular evolution in China. Infect Genet Evol 2014; 27(1): 418-31. 17. Julin K, Mennen S, Sommer AI. Study of virulence in field isolates of infectious panc-reatic necrosis virus obtained from the nort-hern part of Norway. J Fish Dis 2013; 36(2): 89-102. 18. Karlsen M, Andersen L, Blindheim HS, Rimstad E, Nylund A. A naturally occurring substitution in the E2 protein of salmonid alphavirus subtype 3 changes viral fitness. Virus Res 2015; 196(1): 79-86. 19. Kima HS, Yusuff S, Vakharia NV, Evensen O. Interchange of L polymerase protein between two strains of viral hemorrhagic septicemia virus (VHSV) genotype IV alters temperature sensitivities in vitro. Virus Res 2015; 195(1): 203-06. 20. Lauksund S, Greiner-Tollersrud L, Chang JC, Robertsen B. Infectious pancreatic nec-rosis virus proteins VP2, VP3, VP4 and VP5 antagonize IFNa1 promoter activation while VP1 induces IFNa1. Virus Res 2015; 196(1): 113-21. 21. Moriette C, Leberre M, Lamoureux A, Lai TL, Bremont M. Recovery of a recombinant salmonid alphavirus fully attenuated and protective for rainbow trout. J Virol 2006; 80(8):4088-98. 22. Munang’andu MH, Fredriksen NB, Mutoloki S, Brudeseth B, Kuo YT, Marjara SI, Dalmo AR, Evensena O. Comparison of vaccine efficacy for different antigen delivery sys-tems for infectious pancreatic necrosis virus vaccines in Atlantic salmon (Salmo salar L.) in a cohabitation challenge model. Vaccine 2012; 30(27): 4007-16. 23. Nishizawa T, Kinoshita S, Yoshimizu M. An approach for genogrouping of Japanese isolates of aquabirnaviruses in a new ge-nogroup, VII, based on the VP2/NS junction region. J Gen Virol 2005; 86(Pt7): 1973-78. 24. World Organisation for Animal Health (OİE). May 2013. Viral encephalopathy and retino-pathy. Manual of diagnostic tests for aquatic animals. Chapter 2.3.11.Erişim tarihi: 17.12. 2015. http://www.aait.org.cn/web/images/upload/2013/03/24/201303241612484062. pdf 25. Plant PK, Lapatra ES. Advances in fish vac-cine delivery. Dev Comp Immunol 2011; 35(12): 1256-62. 26. Rimstad E, Mjaaland S. Infectious salmon anaemia virus. APMIS 2002; 110(4): 273-82. 27. Santi N, Song H, Vakharia NV, Evensen O. Infectious pancreatic necrosis virus VP5 is dispensable for virulence and persistence. J Virol 2005; 79(14): 9206-16. 28. Song H, Santi N, Evensen O, Vakharia NV. Molecular determinants of infectious pancre-atic necrosis virus virulence and cell culture adaptation. J Virol 2005; 79 (16):10289-99. 29. Yao K, Vakharia NV. Generation of infecti-ous pancreatic necrosis virus from cloned cDNA. J Virol 1998; 72(11); 8913-20. 30. Takizawa N, Adachi K, Kobayashi N. Estab-lishment of reverse genetics system of beta- nodavirus for the efficient recovery of infecti-ous particles. J Virol Methods 2008; 151(2): 271-6. 31. Tam TP, Hoat CP, Hoa HTB, Hien TTN. Evaluation of the pathogenicity and immun response of nervous necrosis virus isolated in Vietnam. J Agr Sci Tech 2014; 4(1): 315-22. 32. Thoulouze MI, Bouguyon E, Carpentier C, Bremont M. Essential role of the NV protein of novirhabdovirus for pathogenicity in rain-bow trout. J Virol 2004; 78(8): 4098-107. 33. Toro-Ascuy D, Tambley C, Beltran C, Mas-cayano C, Sandoval N, Olivares E, Medina AR, Spencer E, Martína SCM. Development of a reverse genetic system for infectious salmon anemia virus: rescue of recombinant fluorescent virus by using salmon internal transcribed spacer region 1 as a novel pro-moter. Appl Environ Microbiol 2015; 81(4): 1210-24.
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Details
| Journal Section | Articles |
|---|---|
| Authors | |
| Publication Date | December 15, 2017 |
| Submission Date | February 2, 2016 |
| Acceptance Date | February 14, 2016 |
| Published in Issue | Year 2017 Volume: 14 Issue: 3 |
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https://dergipark.org.tr/tr/download/journal-file/20610
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